(Q54979591)

14 June 2018

title

Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility. (English)

1 reference

14 June 2018

0 references

1 reference

8

Miho Iijima

1 reference

14 June 2018

author name string

Atsushi Igarashi

1

1 reference

14 June 2018

Kie Itoh

2

1 reference

14 June 2018

Tatsuya Yamada

3

1 reference

14 June 2018

Yoshihiro Adachi

4

1 reference

14 June 2018

Takashi Kato

5

1 reference

14 June 2018

Hiromi Sesaki

6

1 reference

14 June 2018

Daisuke Murata

7

1 reference

14 June 2018

language of work or name

English

0 references

publication date

7 May 2018

1 reference

14 June 2018

Journal of Biological Chemistry

published in

1 reference

14 June 2018

describes a project that uses

volume

293

0 references

issue

24

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page(s)

9292-9300

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ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6005449/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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AKT/PKB Signaling: Navigating the Network

4 October 2018

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Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization

4 October 2018

1 reference

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Functional diversity of astrocytes in neural circuit regulation

4 October 2018

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4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

The PTEN protein: cellular localization and post-translational regulation

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

A new class of cancer-associated PTEN mutations defined by membrane translocation defects

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Immunocytochemical markers of neuronal maturation in human diagnostic neuropathology

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Brain patterning perturbations following PTEN loss

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

New avenues for anti-epileptic drug discovery and development

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Pentylenetetrazol (PTZ) kindling model of epilepsy

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN signaling in autism spectrum disorders

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

The functions and regulation of the PTEN tumour suppressor

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Different conformations of phosphatase and tensin homolog, deleted on chromosome 10 (PTEN) protein within the nucleus and cytoplasm of neurons

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN loss in the continuum of common cancers, rare syndromes and mouse models.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Astrocyte heterogeneity: an underappreciated topic in neurobiology

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Faithfull modeling of PTEN loss driven diseases in the mouse

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN hamartoma tumor syndrome: an overview

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN signaling in brain: neuropathology and tumorigenesis.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN and the PI3-kinase pathway in cancer

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

The nuclear affairs of PTEN.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Essential role for nuclear PTEN in maintaining chromosomal integrity

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Ubiquitination regulates PTEN nuclear import and tumor suppression

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN enters the nuclear age.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Pten regulates neuronal arborization and social interaction in mice

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Temporal and spatial regulation of chemotaxis

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Chemical models of epilepsy with some reference to their applicability in the development of anticonvulsants

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005449

Nuclear PTEN: a tale of many tails

4 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29735527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.RA118.002356

1 reference

14 June 2018

release_dz5ve5xxsrerfa62ngnlfedak4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dz5ve5xxsrerfa62ngnlfedak4

mapped directly with Wikidata item

24 November 2022

based on heuristic

0 references

1 reference

14 June 2018