(Q55239504)

28 June 2018

title

High levels of cytoplasmic HTLV-1 Tax mutant proteins retain a Tax-NF-kappaB-CBP ternary complex in the cytoplasm. (English)

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28 June 2018

Human T-lymphotropic virus 1

main subject

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3

Mordechai Aboud

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28 June 2018

author name string

Inbal Azran

series ordinal

1

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28 June 2018

Kuan-Teh Jeang

series ordinal

2

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28 June 2018

language of work or name

English

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publication date

1 June 2005

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28 June 2018

published in

Oncogene

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28 June 2018

volume

24

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28 June 2018

issue

28

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28 June 2018

page(s)

4521-4530

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28 June 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208645

exact match

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cites work

HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration

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Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity

21 January 2018

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I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

21 January 2018

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Regulation of gene expression by HTLV-I Tax protein

21 January 2018

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Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300

21 January 2018

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Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

21 January 2018

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Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding

21 January 2018

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Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation

21 January 2018

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The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta

21 January 2018

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Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

21 January 2018

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CREB-binding protein/p300 are transcriptional coactivators of p65

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Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivation

21 January 2018

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IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

21 January 2018

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p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex

21 January 2018

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Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappa B proteins for transcriptional activation

21 January 2018

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Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling

21 January 2018

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Characterization of mRNA expression of IkappaB alpha and NF-kappaB subfamilies in primary adult T-cell leukemia cells

21 January 2018

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Functional activities of the human T-cell leukemia virus type I Tax oncoprotein: cellular signaling through NF-kappa B.

21 January 2018

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Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation

21 January 2018

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HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene

21 January 2018

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PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner

21 January 2018

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Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

21 January 2018

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

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NF-kappaB at the crossroads of life and death

21 January 2018

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To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

21 January 2018

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Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.

21 January 2018

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

21 January 2018

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Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex

21 January 2018

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

21 January 2018

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Clastogenic effect of the human T-cell leukemia virus type I Tax oncoprotein correlates with unstabilized DNA breaks

21 January 2018

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Induction of micronuclei by HTLV-I Tax: a cellular assay for function

21 January 2018

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Human T-cell leukemia virus type I and adult T-cell leukemia

21 January 2018

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Trans-activator Tax of human T-cell leukemia virus type 1 enhances mutation frequency of the cellular genome

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Human T-cell leukemia virus type I oncoprotein Tax represses Smad-dependent transforming growth factor beta signaling through interaction with CREB-binding protein/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

The long terminal repeats of human immunodeficiency virus type-1 and human T-cell leukemia virus type-I are activated by 12-O-tetradecanoylphorbol-13-acetate through different pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

HTLV-1 Tax enhances NF-kappa B2 expression and binds to the products p52 and p100, but does not suppress the inhibitory function of p100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Cell cycle dysregulation by HTLV-I: role of the tax oncoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Activators and target genes of Rel/NF-kappaB transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Human T cell leukemia virus type 1 tax protein increases NF-kappa B dimer formation and antagonizes the inhibitory activity of the I kappa B alpha regulatory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Transcriptional activation by NF-kappaB requires multiple coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

NF-kappaB signaling pathways in mammalian and insect innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Tax protein of HTLV-1 inhibits CBP/p300-mediated transcription by interfering with recruitment of CBP/p300 onto DNA element of E-box or p53 binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Activation of simian virus 40 promoter by HTLV-I Tax protein: role of NF-kappaB and CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Activation of HTLV-I long terminal repeat by stress-inducing agents and protection of HTLV-I-infected T-cells from apoptosis by the viral tax protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Sp1-p53 heterocomplex mediates activation of HTLV-I long terminal repeat by 12-O-tetradecanoylphorbol-13-acetate that is antagonized by protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Evidence that protein kinase A activity is required for the basal and tax-stimulated transcriptional activity of human T-cell leukemia virus type-I long terminal repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Binding of the human T-cell leukemia virus Tax protein to the coactivator CBP interferes with CBP-mediated transcriptional control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208645

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

21 January 2018

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The role of NF-kappaB in the regulation of cell stress responses

21 January 2018

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I kappa B proteins: structure, function and regulation

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Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer

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Leukemogenesis of adult T-cell leukemia

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HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

21 January 2018

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Howard Temin memorial lectureship. Molecular biology of HTLV-1: deregulation of host cell gene expression and cell cycle

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Multiple viral strategies of HTLV-1 for dysregulation of cell growth control

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

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The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

21 January 2018

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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

21 January 2018

1 reference

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The human T-cell leukemia virus type 1 transactivator protein Tax colocalizes in unique nuclear structures with NF-kappaB proteins

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7 January 2021

Transdominant human T-cell lymphotropic virus type I TAX1 mutant that fails to localize to the nucleus

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Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a

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Cytoplasmic forms of human T-cell leukemia virus type 1 Tax induce NF-kappaB activation

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Identifiers

DOI

10.1038/SJ.ONC.1208645

1 reference

28 June 2018

Dimensions Publication ID

0 references

1 reference

28 June 2018