(Q55282369)

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Endocannabinoids

scholarly article from 1998

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6 December 2019

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Endocannabinoids (English)

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6 December 2019

endocannabinoids

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Vincenzo Di Marzo

3

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6 December 2019

Raphael Mechoulam

1

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R Mechoulam

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E Fride

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1 October 1998

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6 December 2019

European Journal of Pharmacology

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6 December 2019

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6 December 2019

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6 December 2019

(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability

1 reference

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7 January 2021

An efficient new cannabinoid antiemetic in pediatric oncology

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7 January 2021

Pharmacological and behavioral evaluation of alkylated anandamide analogs

1 reference

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7 January 2021

Bradykinin Stimulates Arachidonic Acid Release Through the Sequential Actions of an sn-1 Diacylglycerol Lipase and a Monoacylglycerol Lipase

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7 January 2021

The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine.

1 reference

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7 January 2021

Cannabinoid receptors and their endogenous agonist, anandamide

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7 January 2021

Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides.

1 reference

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7 January 2021

Functional role of high-affinity anandamide transport, as revealed by selective inhibition

1 reference

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7 January 2021

An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity

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7 January 2021

Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells

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7 January 2021

Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes

1 reference

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7 January 2021

Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells

1 reference

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7 January 2021

Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus.

1 reference

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7 January 2021

Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation.

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7 January 2021

Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide

1 reference

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7 January 2021

The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism

1 reference

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7 January 2021

Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP.

1 reference

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7 January 2021

Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain.

1 reference

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7 January 2021

Influence of cannabinoids on electrically evoked dopamine release and cyclic AMP generation in the rat striatum.

1 reference

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7 January 2021

Potentiation of anandamide hypotension by the transport inhibitor, AM404

1 reference

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7 January 2021

Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice

1 reference

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7 January 2021

Chemical characterization of a family of brain lipids that induce sleep

1 reference

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7 January 2021

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

1 reference

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7 January 2021

Cannabinoid ligand-receptor signaling in the mouse uterus

1 reference

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7 January 2021

The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Cannabinoids enhance human B-cell growth at low nanomolar concentrations

1 reference

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7 January 2021

Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Production and physiological actions of anandamide in the vasculature of the rat kidney.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

A novel probe for the cannabinoid receptor

1 reference

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7 January 2021

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

1 reference

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7 January 2021

Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions

1 reference

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7 January 2021

'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance.

1 reference

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7 January 2021

Biochemistry of the endogenous ligands of cannabinoid receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

1 reference

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7 January 2021

Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide

1 reference

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7 January 2021

Brain cannabinoids in chocolate.

1 reference

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7 January 2021

Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation.

1 reference

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7 January 2021

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide

1 reference

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7 January 2021

Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons

1 reference

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7 January 2021

Cannabinoid receptors and their endogenous agonists.

1 reference

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7 January 2021

Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction

1 reference

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7 January 2021

Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat.

1 reference

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7 January 2021

Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics.

1 reference

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7 January 2021

Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines

1 reference

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7 January 2021

Anandamides: tolerance and cross-tolerance to delta 9-tetrahydrocannabinol

1 reference

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7 January 2021

Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent.

1 reference

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7 January 2021

Developmental aspects of anandamide: ontogeny of response and prenatal exposure

1 reference

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7 January 2021

Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice.

1 reference

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7 January 2021

Anandamide may mediate sleep induction

1 reference

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7 January 2021

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

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7 January 2021

Molecular cloning of a human cannabinoid receptor which is also expressed in testis

1 reference

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7 January 2021

The effects of cannabinoids and other CNS depressants on cell membrane models

1 reference

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7 January 2021

Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor.

1 reference

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7 January 2021

Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand

1 reference

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7 January 2021

Behavioural pharmacology of 5-HT3 receptor antagonists: a critical update on therapeutic potential

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7 January 2021

The non-antiemetic uses of serotonin 5-HT3 receptor antagonists. Clinical pharmacology and therapeutic applications

1 reference

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7 January 2021

The CB1 cannabinoid receptor antagonist SR 141716A affects A9 dopamine neuronal activity in the rat

1 reference

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7 January 2021

Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor

1 reference

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7 January 2021

Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor

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7 January 2021

Early changes in inositol lipids and their metabolites induced by platelet-derived growth factor in quiescent Swiss mouse 3T3 cells

1 reference

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7 January 2021

Cannabinoid receptor localization in brain

1 reference

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7 January 2021

Cannabinoid inhibition of adenylate cyclase: relative activity of constituents and metabolites of marihuana.

1 reference

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7 January 2021

Pharmacology of cannabinoid receptors

1 reference

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7 January 2021

Stereochemical effects of 11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor

1 reference

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7 January 2021

Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes.

1 reference

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7 January 2021

Distribution of anandamide amidohydrolase in rat tissues with special reference to small intestine.

1 reference

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7 January 2021

Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh

1 reference

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7 January 2021

Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C.

1 reference

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7 January 2021

Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor.

1 reference

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7 January 2021

High-performance liquid chromatography and fluorometric detection of arachidonylethanolamide (anandamide) and its analogues, derivatized with 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulp honyl-2,1 ,3- benzoxadiazole (DBD-COCl).

1 reference

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7 January 2021

Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty-acid amide hydrolase.

1 reference

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7 January 2021

Alterations of fatty acyl turnover in macrophage glycerolipids induced by stimulation. Evidence for enhanced recycling of arachidonic acid

1 reference

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7 January 2021

cis-9,10-octadecenoamide, an endogenous sleep-inducing CNS compound, inhibits lymphocyte proliferation

1 reference

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7 January 2021

A hypothesis about the endogenous analogue of general anesthesia

1 reference

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7 January 2021

The endogenous cannabinoid receptor agonist anandamide impairs memory in rats

1 reference

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7 January 2021

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1 reference

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7 January 2021

Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’

1 reference

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7 January 2021

Hashish. I. The structure of cannabidiol

1 reference

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7 January 2021

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1 reference

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7 January 2021

Molecular characterization of a peripheral receptor for cannabinoids

1 reference

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7 January 2021

Suppression of interleukin-2 by the putative endogenous cannabinoid 2-arachidonyl-glycerol is mediated through down-regulation of the nuclear factor of activated T cells

1 reference

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7 January 2021

Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits

1 reference

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7 January 2021

Pharmacology of marijuana

1 reference

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7 January 2021

Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia.

1 reference

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7 January 2021

Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries.

1 reference

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7 January 2021

Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation

1 reference

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7 January 2021

Anandamide and endothelium-derived hyperpolarizing factor act via a common vasorelaxant mechanism in rat mesentery

1 reference

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7 January 2021

Endocannabinoids: a new class of vasoactive substances

1 reference

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7 January 2021

An endogenous cannabinoid as an endothelium-derived vasorelaxant

1 reference

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7 January 2021

Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia.

1 reference

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7 January 2021

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

1 reference

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7 January 2021

Potent Anandamide Analogs: The Effect of Changing the Length and Branching of the End Pentyl Chain

1 reference

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7 January 2021

N-acylated glycerophospholipids and their derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

The N-acylation-phosphodiesterase pathway and cell signalling

1 reference

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7 January 2021

Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction

1 reference

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7 January 2021

Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide.

1 reference

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7 January 2021

Bioactive long chain N-acylethanolamines in five species of edible bivalve molluscs. Possible implications for mollusc physiology and sea food industry

1 reference

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7 January 2021

Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor

1 reference

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7 January 2021

Intrastriatal injection of cannabinoid receptor agonists induced turning behavior in mice

1 reference

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7 January 2021

A second endogenous cannabinoid that modulates long-term potentiation

1 reference

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7 January 2021

2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities

1 reference

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7 January 2021

Detection of an endogenous cannabimimetic molecule, 2-arachidonoylglycerol, and cannabinoid CB1 receptor mRNA in human vascular cells: is 2-arachidonoylglycerol a possible vasomodulator?

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Biphasic effects of anandamide

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Correlation between the psychotropic potency of cannabinoids and their effect on the 1H-NMR spectra of model membranes

1 reference

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7 January 2021

Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Structure-activity analysis of anandamide analogs: relationship to a cannabinoid pharmacophore.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

A possible pathway of phosphoinositide metabolism through EDTA-insensitive phospholipase A1 followed by lysophosphoinositide-specific phospholipase C in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Characterization of anandamide-induced tolerance: comparison to delta 9-THC-induced interactions with dynorphinergic systems

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Effects of anandamide on gestation in pregnant rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Discriminative stimulus effects of anandamide in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Studies on the effects of anandamide in rat hepatic artery

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric determination of anandamide and its analogs in rat brain and peripheral tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900649-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0014-2999(98)00649-9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9831287%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9831287%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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