(Q55463095)

12 July 2018

title

Histone deacetylase inhibitors prime medulloblastoma cells for chemotherapy-induced apoptosis by enhancing p53-dependent Bax activation. (English)

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12 July 2018

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Klaus-Michael Debatin

8

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12 July 2018

Simone Fulda

9

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12 July 2018

Stefan Rutkowski

7

object named as

S Rutkowski

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12 July 2018

author name string

S Häcker

1

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12 July 2018

S Karl

2

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12 July 2018

I Mader

3

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12 July 2018

S Cristofanon

4

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12 July 2018

T Schweitzer

5

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12 July 2018

J Krauss

6

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12 July 2018

language of work or name

English

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publication date

17 January 2011

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12 July 2018

published in

Oncogene

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12 July 2018

volume

30

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12 July 2018

issue

19

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12 July 2018

page(s)

2275-2281

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12 July 2018

https://scigraph.springernature.com/pub.10.1038/onc.2010.599

exact match

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cites work

The Bcl-2 apoptotic switch in cancer development and therapy

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Anticancer activities of histone deacetylase inhibitors

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A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

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Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation.

21 January 2018

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Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

21 January 2018

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Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

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Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

21 January 2018

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Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase

21 January 2018

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Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

21 January 2018

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Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8.

21 January 2018

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MS-275, a potent orally available inhibitor of histone deacetylases--the development of an anticancer agent

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Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response

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The WHO classification of tumors of the nervous system

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Sodium butyrate and tributyrin induce in vivo growth inhibition and apoptosis in human prostate cancer

21 January 2018

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Medulloblastoma: from molecular pathology to therapy

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Prognostic relevance of clinical and biological risk factors in childhood medulloblastoma: results of patients treated in the prospective multicenter trial HIT'91.

21 January 2018

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Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors

21 January 2018

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Acetylation of the DNA binding domain regulates transcription-independent apoptosis by p53.

21 January 2018

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Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations

21 January 2018

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Targeting XIAP Bypasses Bcl-2-Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

21 January 2018

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Histone deacetylase inhibitors: molecular mechanisms of action

21 January 2018

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p53 acetylation is crucial for its transcription-independent proapoptotic functions

21 January 2018

1 reference

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Histone deacetylase inhibitors in cancer therapy

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.599

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12 July 2018

Dimensions Publication ID

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12 July 2018