(Q55514656)

http://europepmc.org/abstract/PMC/6023611

14 July 2018

title

Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair. (English)

1 reference

http://europepmc.org/abstract/PMC/6023611

14 July 2018

1 reference

0 references

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Martin Jínek

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Gerald Schwank

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Nataša Savić

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Femke Cas Ringnalda

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Helen Lindsay

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Mark D. Robinson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jonathan Hall

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Katja Bargsten

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Yizhou Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Dario Neri

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Christian Berk

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

29 May 2018

1 reference

http://europepmc.org/abstract/PMC/6023611

14 July 2018

published in

eLife

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

31 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6023611/fullTextXML

inferred from PubMed Central ID database lookup

cites work

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes.

15 July 2018

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A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

15 July 2018

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15 July 2018

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Post-translational Regulation of Cas9 during G1 Enhances Homology-Directed Repair

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.

15 July 2018

1 reference

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Repair Pathway Choices and Consequences at the Double-Strand Break

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Small molecules enhance CRISPR genome editing in pluripotent stem cells.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Aptamer-guided gene targeting in yeast and human cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Genome-scale CRISPR-Cas9 knockout screening in human cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

PEAR: a fast and accurate Illumina Paired-End reAd mergeR.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

RNA-guided human genome engineering via Cas9

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Comparison of nonhomologous end joining and homologous recombination in human cells.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

ArrayExpress--a public repository for microarray gene expression data at the EBI

15 July 2018

1 reference

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DNA double-strand break repair by homologous recombination

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Nuclear localization signal peptides enhance cationic liposome-mediated gene therapy

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

CrispRVariants charts the mutation spectrum of genome engineering experiments.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

A general method for the covalent labeling of fusion proteins with small molecules in vivo

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA induces homology-directed DNA repair

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6023611

A nuclear localization signal can enhance both the nuclear transport and expression of 1 kb DNA

30 November 2018

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12 December 2020

Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells

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12 December 2020

CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway

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12 December 2020

In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.33761

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29809142%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

29809142

1 reference