(Q56550183)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

title

Genetic and transcriptional evolution alters cancer cell line drug response (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

single cell transcriptomics

16 April 2020

main subject

cell line

0 references

1 reference

A curated database reveals trends in single-cell transcriptomics

https://www.nxn.se/single-cell-studies/data.tsv

7 February 2021

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Aviad Tsherniak

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Francisca Vazquez

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Mahmoud Ghandi

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

30

Todd R Golub

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

29

Rameen Beroukhim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

1

Uri Ben-David

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

8

Joshua Dempster

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

14

Peter Tsvetkov

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Pratiti Bandopadhayay

19

object named as

Pratiti Bandopadhayay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

25

Aaron R Thorner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

27

Matthew Meyerson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

28

Gad Getz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

26

Joshua A Bittker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

author name string

Benjamin Siranosian

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Helen Tang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Yaara Oren

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Kunihiko Hinohara

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Robert Burns

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Anwesha Nag

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Guillaume Kugener

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Beth Cimini

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Anthony Garrity

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Bang Wong

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Chet Birger

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Craig A Strathdee

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Nicholas J Lyons

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Yosef E Maruvka

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Ryan O'Rourke

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Andrew A Tubelli

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

language of work or name

English

0 references

publication date

8 August 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

volume

560

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

page(s)

325-330

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

issue

7718

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

16 April 2020

cell culture

1 reference

A curated database reveals trends in single-cell transcriptomics

7 February 2021

https://www.nxn.se/single-cell-studies/data.tsv

10x Genomics Chromium

1 reference

A curated database reveals trends in single-cell transcriptomics

https://www.nxn.se/single-cell-studies/data.tsv

https://scigraph.springernature.com/pub.10.1038/s41586-018-0409-3

7 February 2021

exact match

0 references

cites work

Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents

1 reference

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7 January 2021

The Economics of Reproducibility in Preclinical Research

1 reference

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7 January 2021

Believe it or not: how much can we rely on published data on potential drug targets?

1 reference

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7 January 2021

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

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7 January 2021

Systematic identification of genomic markers of drug sensitivity in cancer cells

1 reference

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7 January 2021

An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.

1 reference

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7 January 2021

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

1 reference

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7 January 2021

Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.

1 reference

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7 January 2021

Inconsistency in large pharmacogenomic studies

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7 January 2021

Pharmacogenomic agreement between two cancer cell line data sets.

1 reference

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7 January 2021

Reproducible pharmacogenomic profiling of cancer cell line panels.

1 reference

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7 January 2021

A human cell line from a pleural effusion derived from a breast carcinoma

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7 January 2021

MCF-7 cells--changing the course of breast cancer research and care for 45 years

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7 January 2021

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

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7 January 2021

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

1 reference

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7 January 2021

PyClone: statistical inference of clonal population structure in cancer.

1 reference

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7 January 2021

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.

1 reference

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7 January 2021

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.

1 reference

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7 January 2021

High-throughput Phenotyping of Lung Cancer Somatic Mutations

1 reference

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7 January 2021

A method for high-throughput gene expression signature analysis

1 reference

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7 January 2021

Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells

1 reference

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7 January 2021

A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells

1 reference

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7 January 2021

Comprehensive molecular profiling of lung adenocarcinoma

1 reference

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7 January 2021

Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes.

1 reference

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7 January 2021

The Molecular Signatures Database (MSigDB) hallmark gene set collection

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7 January 2021

In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer

1 reference

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7 January 2021

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

1 reference

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7 January 2021

Workflow and metrics for image quality control in large-scale high-content screens

1 reference

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7 January 2021

CellProfiler Analyst: interactive data exploration, analysis and classification of large biological image sets

1 reference

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7 January 2021

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

1 reference

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7 January 2021

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

1 reference

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7 January 2021

Institutional implementation of clinical tumor profiling on an unselected cancer population

1 reference

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7 January 2021

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

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7 January 2021

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

1 reference

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7 January 2021

A framework for variation discovery and genotyping using next-generation DNA sequencing data

1 reference

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7 January 2021

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0409-3

7 January 2021

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0409-3

7 January 2021

Circular binary segmentation for the analysis of array-based DNA copy number data

1 reference

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7 January 2021

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers

1 reference

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7 January 2021

Improved vectors and genome-wide libraries for CRISPR screening

1 reference

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7 January 2021

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

1 reference

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7 January 2021

Adjusting batch effects in microarray expression data using empirical Bayes methods

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7 January 2021

Correlating chemical sensitivity and basal gene expression reveals mechanism of action.

1 reference

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7 January 2021

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

1 reference

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7 January 2021

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

1 reference

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7 January 2021

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

1 reference

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7 January 2021

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

1 reference

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7 January 2021

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

1 reference

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7 January 2021

A Method for Comparing Two Hierarchical Clusterings

1 reference

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7 January 2021

Patient-derived xenografts undergo mouse-specific tumor evolution.

1 reference

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7 January 2021

Absolute quantification of somatic DNA alterations in human cancer

1 reference

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7 January 2021

A genomic instability score in discriminating nonequivalent outcomes of BRCA1/2 mutations and in predicting outcomes of ovarian cancer treated with platinum-based chemotherapy

1 reference

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7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

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7 January 2021

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0409-3

7 January 2021

Consensus coding sequence (CCDS) database: a standardized set of human and mouse protein-coding regions supported by expert curation.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0409-3

7 January 2021

RNA-Seq gene expression estimation with read mapping uncertainty

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0409-3

7 January 2021

Virtual karyotyping of pluripotent stem cells on the basis of their global gene expression profiles

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0409-3

7 January 2021

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30089904

12 December 2020

inferred from PubMed ID database lookup

Estrogen receptor in a human cell line (MCF-7) from breast carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30089904

12 December 2020

inferred from PubMed ID database lookup

STAR: ultrafast universal RNA-seq aligner

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30089904

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41586-018-0409-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30089904%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

1 reference