(Q56897591)

10

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Shizuo Akira

9

object named as

Shizuo Akira

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author name string

Thomas Marichal

1

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Keiichi Ohata

2

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Denis Bedoret

3

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Claire Mesnil

4

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Catherine Sabatel

5

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Kouji Kobiyama

6

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Pierre Lekeux

7

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Fabrice Bureau

11

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Christophe J Desmet

https://scigraph.springernature.com/pub.10.1038/nm.2403

12

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language of work or name

English

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publication date

17 July 2011

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published in

Nature Medicine

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volume

17

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issue

8

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page(s)

996-1002

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exact match

0 references

cites work

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

21 January 2018

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The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity

21 January 2018

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Special regulatory T-cell review: FOXP3 biochemistry in regulatory T cells--how diverse signals regulate suppression

21 January 2018

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The controversial relationship between NLRP3, alum, danger signals and the next-generation adjuvants.

21 January 2018

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Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity

21 January 2018

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Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

21 January 2018

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Local tissue irritating effects and adjuvant activities of calcium phosphate and aluminium hydroxide with different physical properties

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How dying cells alert the immune system to danger

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Sterile inflammation: sensing and reacting to damage

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Genomic DNA released by dying cells induces the maturation of APCs

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Intracellular DNA sensors in immunity

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Pattern recognition receptors and inflammation

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Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide

21 January 2018

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

21 January 2018

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The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

21 January 2018

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RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

21 January 2018

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

21 January 2018

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

21 January 2018

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HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

21 January 2018

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The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway

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A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

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Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

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TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

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Interferon response factor 3 is essential for house dust mite–induced airway allergy

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Cytokine-secreting follicular T cells shape the antibody repertoire

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Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes

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Steady-state and inflammatory dendritic-cell development

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Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection

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Yersinia pestis evades TLR4-dependent induction of IL-12(p40)2 by dendritic cells and subsequent cell migration

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Mutation of DNASE1 in people with systemic lupus erythematosus

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Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA

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Translating innate immunity into immunological memory: implications for vaccine development

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Vaccine adjuvants: putting innate immunity to work

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The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

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Follicular helper T cells: lineage and location

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Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses

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A Toll-like receptor recognizes bacterial DNA

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The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

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Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

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Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

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Cryopyrin activates the inflammasome in response to toxins and ATP

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Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

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Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages

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Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

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12 December 2020

Dendritic cell-derived IL-12p40 homodimer contributes to susceptibility in cutaneous leishmaniasis in BALB/c mice

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Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome

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Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

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12 December 2020

Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release

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12 December 2020

Modulation of the human immune response by the non-toxic and non-pyrogenic adjuvant aluminium hydroxide: effect on antigen uptake and antigen presentation

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12 December 2020