(Q56897833)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22759318%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Preclinical efficacy and immunological safety of FR104, an antagonist anti-CD28 monovalent Fab' antibody (English)

1 reference

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6 February 2020

1 reference

7

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6 February 2020

author name string

N Poirier

1

1 reference

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6 February 2020

C Mary

2

1 reference

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6 February 2020

N Dilek

3

1 reference

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6 February 2020

J Hervouet

4

1 reference

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6 February 2020

D Minault

5

1 reference

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6 February 2020

G Blancho

6

1 reference

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6 February 2020

language of work or name

English

0 references

publication date

3 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22759318%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Transplantation

6 February 2020

published in

1 reference

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6 February 2020

volume

12

1 reference

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6 February 2020

issue

10

1 reference

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6 February 2020

page(s)

2630-2640

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CTLA-4 control over Foxp3+ regulatory T cell function

6 February 2020

cites work

1 reference

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Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance

21 January 2018

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Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

21 January 2018

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Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies

21 January 2018

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Selective CD28 blockade attenuates acute and chronic rejection of murine cardiac allografts in a CTLA-4-dependent manner

21 January 2018

1 reference

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Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.

21 January 2018

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Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.

21 January 2018

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Costimulation couture: a designer approach to regulating autoimmunity

21 January 2018

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

21 January 2018

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Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes

21 January 2018

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T-cell regulation by CD28 and CTLA-4.

21 January 2018

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Costimulation blockade with belatacept in renal transplantation

21 January 2018

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Alternatives to calcineurin inhibition in renal transplantation: belatacept, the first co-stimulation blocker.

21 January 2018

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Interaction of human PD-L1 and B7-1.

21 January 2018

1 reference

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Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

21 January 2018

1 reference

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B7-h2 is a costimulatory ligand for CD28 in human

21 January 2018

1 reference

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A more selective costimulatory blockade of the CD28-B7 pathway.

21 January 2018

1 reference

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CD28-specific immunomodulating antibodies: what can be learned from experimental models?

21 January 2018

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Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression

21 January 2018

1 reference

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Targeted CTLA-4 engagement induces CD4+CD25+CTLA-4high T regulatory cells with target (allo)antigen specificity.

21 January 2018

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TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells

21 January 2018

1 reference

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Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

21 January 2018

1 reference

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The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

21 January 2018

1 reference

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TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors

21 January 2018

1 reference

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All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation

21 January 2018

1 reference

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Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling

21 January 2018

1 reference

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FR255734, a humanized, Fc-Silent, Anti-CD28 antibody, improves psoriasis in the SCID mouse-psoriasis xenograft model

21 January 2018

1 reference

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Differential effect of CD28 versus B7 blockade on direct pathway of allorecognition and self-restricted responses

21 January 2018

1 reference

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Roles of CD28, CTLA4, and inducible costimulator in acute graft-versus-host disease in mice

21 January 2018

1 reference

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Anti-CD28 antibody-induced kidney allograft tolerance related to tryptophan degradation and TCR class II B7 regulatory cells

21 January 2018

1 reference

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Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation

21 January 2018

1 reference

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Selective blockade of CD28 and not CTLA-4 with a single-chain Fv-alpha1-antitrypsin fusion antibody

21 January 2018

1 reference

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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

21 January 2018

1 reference

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Relative over-reactivity of human versus chimpanzee lymphocytes: implications for the human diseases associated with immune activation

21 January 2018

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Loss of Siglec expression on T lymphocytes during human evolution

21 January 2018

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Humanized mice in translational biomedical research

21 January 2018

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Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice

21 January 2018

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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

21 January 2018

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Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells

21 January 2018

1 reference

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Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras

21 January 2018

1 reference

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A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).

21 January 2018

1 reference

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10.1111/J.1600-6143.2012.04164.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22759318%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference