(Q56899105)

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SNPs upstream of the minimal promoter control IL-2 expression and are candidates for the autoimmune disease-susceptibility locus Aod2/Idd3/Eae3

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SNPs upstream of the minimal promoter control IL-2 expression and are candidates for the autoimmune disease-susceptibility locus Aod2/Idd3/Eae3 (English)

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susceptibility locus

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based on heuristic

inferred from title

object named as

S Diehl

5

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author name string

R del Rio

1

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R Noubade

2

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M Subramanian

3

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N Saligrama

4

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M Rincon

6

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C Teuscher

7

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publication date

17 January 2008

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Genes and Immunity

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9

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2

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115-121

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Transcriptional repression of interleukin-2 in human systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Transgenic mice expressing constitutive levels of IL-2 in islet beta cells develop diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

A function for interleukin 2 in Foxp3-expressing regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Allelic expression and interleukin-2 polymorphisms in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Risk alleles for multiple sclerosis identified by a genomewide study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Aod2, the locus controlling development of atrophy in neonatal thymectomy-induced autoimmune ovarian dysgenesis, co-localizes with Il2, Fgfb, and Idd3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Interacting quantitative trait loci control loss of peripheral tolerance and susceptibility to autoimmune ovarian dysgenesis after day 3 thymectomy in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Identification of Bphs, an autoimmune disease locus, as histamine receptor H1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Aod1 controlling day 3 thymectomy-induced autoimmune ovarian dysgenesis in mice encompasses two linked quantitative trait loci with opposing allelic effects on disease susceptibility

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

21 January 2018

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

Inflammation but not autoimmunity occurs in transgenic mice expressing constitutive levels of interleukin-2 in islet beta cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterizations of candidate genes for IDD susceptibility from the diabetes-prone NOD mouse strain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

DIFFERENTIAL GLYCOSYLATION OF INTERLEUKIN 2, THE MOLECULAR BASIS FOR THE NOD Idd3 TYPE 1 DIABETES GENE?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

Experimental allergic orchitis in mice. II. Association of disease susceptibility with the locus controlling Bordetella pertussis-induced sensitivity to histamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

Physical mapping of the autoimmune disease susceptibility locus, Bphs: co-localization with a cluster of genes from the TNF receptor superfamily on mouse chromosome 6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364455

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/SJ.GENE.6364455

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