(Q56957525)

Ramón Lorenzo-Redondo

2

0 references

Cecilio Lopez-Galindez

Cecilio López-Galíndez

3

0 references

Esteban Domingo Solans

Esteban Domingo

5

0 references

Celia Perales

1

Celia Perales

0 references

author name string

Miguel Angel Martínez

The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate.

4

0 references

publication date

November 2010

0 references

published in

Future Virology

0 references

volume

5

0 references

issue

6

0 references

page(s)

679-698

0 references

cites work

1 reference

In vitro site-directed mutagenesis: Generation and properties of an infectious extracistronic mutant of bacteriophage Qβ

21 January 2018

1 reference

Nucleotide sequence heterogeneity of an RNA phage population.

21 January 2018

1 reference

Rapid evolution of RNA genomes

21 January 2018

1 reference

Contributions of vesicular stomatitis virus to the understanding of RNA virus evolution

21 January 2018

1 reference

The quasispecies nature and biological implications of the hepatitis C virus

21 January 2018

1 reference

Selforganization of matter and the evolution of biological macromolecules

21 January 2018

1 reference

The 30th anniversary of quasispecies. Meeting on 'Quasispecies: past, present and future'.

21 January 2018

1 reference

Unfinished stories on viral quasispecies and Darwinian views of evolution.

21 January 2018

1 reference

The origin of genetic information: viruses as models

21 January 2018

1 reference

On the nature of virus quasispecies

21 January 2018

1 reference

21 January 2018

Quasispecies made simple

1 reference

Quasispecies Theory in Virology.

21 January 2018

1 reference

Is the quasispecies concept relevant to RNA viruses?

21 January 2018

1 reference

The RNA virus quasispecies: fact or fiction?

21 January 2018

1 reference

Exact solution of the Eigen model with general fitness functions and degradation rates

21 January 2018

1 reference

Adaptive value of high mutation rates of RNA viruses: separating causes from consequences

21 January 2018

1 reference

21 January 2018

What is a quasispecies?

1 reference

Coinfection and superinfection in patients with long-term, nonprogressive HIV-1 disease

21 January 2018

1 reference

Dual HIV-1 infection associated with rapid disease progression

21 January 2018

1 reference

Evidence for frequent reinfection with human immunodeficiency virus type 1 of a different subtype

21 January 2018

1 reference

Genetic diversity in RNA virus quasispecies is controlled by host-virus interactions

21 January 2018

1 reference

Antigenic variation in lentiviral diseases

21 January 2018

1 reference

21 January 2018

1 reference

Genetic variability: The key problem in the prevention and therapy of RNA‐based virus infections

21 January 2018

1 reference

Rapid viral quasispecies evolution: implications for vaccine and drug strategies

21 January 2018

1 reference

Competition-colonization dynamics in an RNA virus

21 January 2018

1 reference

Collective properties of evolving molecular quasispecies

21 January 2018

1 reference

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

21 January 2018

1 reference

Darwinian evolution of prions in cell culture

21 January 2018

1 reference

Location and primary structure of a major antigenic site for poliovirus neutralization

21 January 2018

1 reference

An inducible mammalian amber suppressor: propagation of a poliovirus mutant.

21 January 2018

1 reference

Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase

21 January 2018

1 reference

Sequential structures provide insights into the fidelity of RNA replication

21 January 2018

1 reference

Molecular basis of fidelity of DNA synthesis and nucleotide specificity of retroviral reverse transcriptases

21 January 2018

1 reference

Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective

21 January 2018

1 reference

Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin

21 January 2018

1 reference

Mutations that increase DNA binding by the processivity factor of herpes simplex virus affect virus production and DNA replication fidelity

21 January 2018

1 reference

Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice

21 January 2018

1 reference

Evolvability is a selectable trait

21 January 2018

1 reference

Mutational fitness effects in RNA and single-stranded DNA viruses: common patterns revealed by site-directed mutagenesis studies

21 January 2018

1 reference

Viral Quasispecies: Dynamics, Interactions, and Pathogenesis**Dedicated to Manfred Eigen on the occasion of his 80th birthday, for the insights that his pioneer studies have represented for virology

21 January 2018

1 reference

Quasispecies and its impact on viral hepatitis

21 January 2018

1 reference

Future prospects for the treatment of rapidly evolving viral pathogens: insights from evolutionary biology

21 January 2018

1 reference

A comparison of viral RNA-dependent RNA polymerases

21 January 2018

1 reference

Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase

21 January 2018

1 reference

High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.

21 January 2018

1 reference

Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing

21 January 2018

1 reference

Targeting HIV: antiretroviral therapy and development of drug resistance.

21 January 2018

1 reference

Environment determines fidelity for an RNA virus replicase

21 January 2018

1 reference

DNA polymerase fidelity: comparing direct competition of right and wrong dNTP substrates with steady state and pre-steady state kinetics

21 January 2018

1 reference

Recombination: Multiply infected spleen cells in HIV patients

21 January 2018

1 reference

High rate of recombination throughout the human immunodeficiency virus type 1 genome

21 January 2018

1 reference

Multidrug-resistant variants of HIV type 1 (HIV-1) can exist in cells as defective quasispecies and be rescued by superinfection with other defective HIV-1 variants

21 January 2018

1 reference

APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis

21 January 2018

1 reference

Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo

21 January 2018

1 reference

Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis

21 January 2018

1 reference

Hypermutagenesis of RNA using human immunodeficiency virus type 1 reverse transcriptase and biased dNTP concentrations

21 January 2018

1 reference

Highly diversified multiply drug-resistant HIV-1 quasispecies in PBMCs: a case report.

21 January 2018

1 reference

Histochemical Demonstration of Enzymes Separated by Zone Electrophoresis in Starch Gels

21 January 2018

1 reference

MULTIPLE FORMS OF ENZYMES: TISSUE, ONTOGENETIC, AND SPECIES SPECIFIC PATTERNS.

21 January 2018

1 reference

Enzyme Polymorphisms in Man

21 January 2018

1 reference

Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution

21 January 2018

1 reference

Viral population estimation using pyrosequencing

21 January 2018

1 reference

Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo

21 January 2018

1 reference

Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance

21 January 2018

1 reference

Minority human immunodeficiency virus type 1 variants in antiretroviral-naive persons with reverse transcriptase codon 215 revertant mutations.

21 January 2018

1 reference

DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations

21 January 2018

1 reference

Characterization of quasispecies of pandemic 2009 influenza A virus (A/H1N1/2009) by de novo sequencing using a next-generation DNA sequencer.

21 January 2018

1 reference

The feasibility of using high resolution genome sequencing of influenza A viruses to detect mixed infections and quasispecies

21 January 2018

1 reference

An enhanced single base extension technique for the analysis of complex viral populations

21 January 2018

1 reference

Ultra-deep pyrosequencing of hepatitis B virus quasispecies from nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI)-treated patients and NRTI-naive patients.

21 January 2018

1 reference

Use of massively parallel ultradeep pyrosequencing to characterize the genetic diversity of hepatitis B virus in drug-resistant and drug-naive patients and to detect minor variants in reverse transcriptase and hepatitis B S antigen

21 January 2018

1 reference

Predicting the antigenic structure of the pandemic (H1N1) 2009 influenza virus hemagglutinin

21 January 2018

1 reference

Evolutionary trends of A(H1N1) influenza virus hemagglutinin since 1918

21 January 2018

1 reference

Evolvability of an RNA virus is determined by its mutational neighbourhood

21 January 2018

1 reference

Self-replication with errors. A model for polynucleotide replication.

21 January 2018

1 reference

Monitoring sequence space as a test for the target of selection in viruses.

21 January 2018

1 reference

21 January 2018

Molecular quasi-species

1 reference

Preextinction viral RNA can interfere with infectivity

21 January 2018

1 reference

Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses

21 January 2018

1 reference

Suppression of viral infectivity through lethal defection

21 January 2018

1 reference

Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding

21 January 2018

1 reference

Complete alanine scanning of intersubunit interfaces in a foot-and-mouth disease virus capsid reveals critical contributions of many side chains to particle stability and viral function.

21 January 2018

1 reference

Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants

21 January 2018

1 reference

Correlation between amount of virus with altered nucleotide sequence and the monkey test for acceptability of oral poliovirus vaccine

21 January 2018

1 reference

Suppression of lymphocytic choriomeningitis virus--induced growth hormone deficiency syndrome by disease-negative virus variants

21 January 2018

1 reference

Long-term transmission of defective RNA viruses in humans and Aedes mosquitoes

21 January 2018

1 reference

Initial fitness recovery of HIV-1 is associated with quasispecies heterogeneity and can occur without modifications in the consensus sequence

21 January 2018

1 reference

Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe

21 January 2018

1 reference

Hidden virulence determinants in a viral quasispecies in vivo

21 January 2018

1 reference

Fine-tuning translation kinetics selection as the driving force of codon usage bias in the hepatitis A virus capsid

21 January 2018

1 reference

THE NATURAL-SELECTION THEORY OF ANTIBODY FORMATION

21 January 2018

1 reference

Memory in viral quasispecies

21 January 2018

1 reference

Fitness increase of memory genomes in a viral quasispecies

21 January 2018

1 reference

Duration and fitness dependence of quasispecies memory

21 January 2018

1 reference

The red queen reigns in the kingdom of RNA viruses

21 January 2018

1 reference

Synchronous loss of quasispecies memory in parallel viral lineages: a deterministic feature of viral quasispecies

21 January 2018

1 reference

Reproducible nonlinear population dynamics and critical points during replicative competitions of RNA virus quasispecies.

21 January 2018

1 reference

Persistence of foot-and-mouth disease virus in cell culture revisited: implications for contingency in evolution.

21 January 2018

1 reference

Contingent neutrality in competing viral populations

21 January 2018

1 reference

Evolution of digital organisms at high mutation rates leads to survival of the flattest

21 January 2018

1 reference

The fittest versus the flattest: experimental confirmation of the quasispecies effect with subviral pathogens.

21 January 2018

1 reference

Selection for robustness in mutagenized RNA viruses

21 January 2018

1 reference

Resistance of virus to extinction on bottleneck passages: study of a decaying and fluctuating pattern of fitness loss

21 January 2018

1 reference

Transition between stochastic evolution and deterministic evolution in the presence of selection: general theory and application to virology.

21 January 2018

1 reference

Memory in retroviral quasispecies: experimental evidence and theoretical model for human immunodeficiency virus

21 January 2018

1 reference

Minority memory genomes can influence the evolution of HIV-1 quasispecies in vivo.

21 January 2018

1 reference

Phenotypic mixing and hiding may contribute to memory in viral quasispecies

21 January 2018

1 reference

A single amino acid substitution in nonstructural protein 3A can mediate adaptation of foot-and-mouth disease virus to the guinea pig.

21 January 2018

1 reference

Genetic and phenotypic variability during replication of foot-and-mouth disease virus in swine

21 January 2018

1 reference

Genetic and phenotypic variation of foot-and-mouth disease virus during serial passages in a natural host.

21 January 2018

1 reference

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

21 January 2018

1 reference

Guinea pig-adapted foot-and-mouth disease virus with altered receptor recognition can productively infect a natural host

21 January 2018

1 reference

The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies

21 January 2018

1 reference

Evolution of hepatitis C viral quasispecies and hepatic injury in perinatally infected children followed prospectively

21 January 2018

1 reference

The origin of quasispecies: cause or consequence of chronic hepatitis C viral infection?

21 January 2018

1 reference

Hepatitis C virus resistance to antiviral therapy.

21 January 2018

1 reference

Mechanisms of antiviral treatment efficacy and failure in chronic hepatitis C.

21 January 2018

1 reference

Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome

21 January 2018

1 reference

Role of the mutant spectrum in adaptation and replication of West Nile virus

21 January 2018

1 reference

Genetic variation in West Nile virus from naturally infected mosquitoes and birds suggests quasispecies structure and strong purifying selection

21 January 2018

1 reference

Changes in human immunodeficiency virus type 1 fitness and genetic diversity during disease progression

21 January 2018

1 reference

Time to hit HIV, early and hard.

21 January 2018

1 reference

Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop

21 January 2018

1 reference

HIV vaccine design: insights from live attenuated SIV vaccines

21 January 2018

1 reference

Mechanism of protection of live attenuated simian immunodeficiency virus: coevolution of viral and immune responses

21 January 2018

1 reference

Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants.

21 January 2018

1 reference

Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys

21 January 2018

1 reference

Evidence of the coevolution of antigenicity and host cell tropism of foot-and-mouth disease virus in vivo

21 January 2018

1 reference

Evolution of cell recognition by viruses

21 January 2018

1 reference

Evolution of cell recognition by viruses: a source of biological novelty with medical implications

21 January 2018

1 reference

The effect of vaccination on the evolution and population dynamics of avian paramyxovirus-1.

21 January 2018

1 reference

Recovery of APOBEC3-edited human immunodeficiency virus G->A hypermutants by differential DNA denaturation PCR.

21 January 2018

1 reference

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs

21 January 2018

1 reference

Quasispecies-like behavior observed in catalytic RNA populations evolving in a test tube.

21 January 2018

1 reference

Metapopulation dynamics and spatial heterogeneity in cancer

21 January 2018

1 reference

An error catastrophe in cancer?

21 January 2018

1 reference

Mechanisms of viral emergence

21 January 2018

1 reference

Emergence and re-emergence of viral diseases of the central nervous system

21 January 2018

1 reference

Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates

21 January 2018

1 reference