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Cardiotoxicity with vascular endothelial growth factor inhibitor therapy
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title
Cardiotoxicity with vascular endothelial growth factor inhibitor therapy
(English)
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author
Rhian Touyz
object named as
Rhian M Touyz
series ordinal
1
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author name string
Joerg Herrmann
series ordinal
2
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language of work or name
English
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publication date
2018
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published in
npj Precision Oncology
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volume
2
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issue
1
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page(s)
13
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copyright license
Creative Commons Attribution 4.0 International
start time
8 May 2018
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April 2022 Public Data File from Crossref
copyright status
copyrighted
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exact match
https://scigraph.springernature.com/pub.10.1038/s41698-018-0056-z
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cites work
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clini
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Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism
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Incidence and risk of cardiotoxicity in cancer patients treated with targeted therapies.
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AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System.
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Metabolic Remodeling in Diabetic Cardiomyopathy
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A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate
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Remodeling of glucose metabolism precedes pressure overload-induced left ventricular hypertrophy: review of a hypothesis
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Congestive heart failure with vascular endothelial growth factor receptor tyrosine kinase inhibitors
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Metformin and its effects on myocardial dimension and left ventricular hypertrophy in normotensive patients with coronary heart disease (the MET-REMODEL study): rationale and design of the MET-REMODEL study.
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Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging
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Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567): an open-label, randomised, multicentre, phase 2 study
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2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines
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Angiogenesis and cardiac hypertrophy: maintenance of cardiac function and causative roles in heart failure
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Cardiac metabolism in heart failure: implications beyond ATP production.
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Metabolic remodeling in chronic heart failure
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Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity
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Mechanisms of cardiac dysfunction in obstructive sleep apnea
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Effects of novel angiogenesis inhibitors for the treatment of cancer on the cardiovascular system: focus on hypertension
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Metformin protects against doxorubicin-induced cardiotoxicity: involvement of the adiponectin cardiac system.
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Incidence and risk of congestive heart failure in patients with renal and nonrenal cell carcinoma treated with sunitinib.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
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Myocardial perfusion by myocardial contrast echocardiography and endothelial dysfunction in obstructive sleep apnea
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PubMed Central
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Metformin improves cardiac function in a nondiabetic rat model of post-MI heart failure.
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PubMed Central
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2 November 2018
Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
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VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation
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PubMed Central
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Risk of surgery following recent myocardial infarction
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Congestive heart failure risk in patients with breast cancer treated with bevacizumab.
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Hypothyroidism and hypertension
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PubMed Central
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retrieved
2 November 2018
Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Frequency and management of troponin I elevation in patients treated with molecular targeted therapies in phase I trials.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
PGC-1 coactivators in cardiac development and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Subclinical hypothyroidism and the risk of coronary heart disease and mortality
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
The lack of target specificity of small molecule anticancer kinase inhibitors is correlated with their ability to damage myocytes in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Abnormal myocardial capillary density in apical hypertrophic cardiomyopathy can be assessed by myocardial contrast echocardiography.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Does coronary flow trump coronary anatomy?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Cardiovascular toxicity following sunitinib therapy in metastatic renal cell carcinoma: a multicenter analysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Obstructive sleep apnoea and its cardiovascular consequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Severe obstructive sleep apnoea exacerbates the microvascular impairment in very mild hypertensives.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Metformin induces cardioprotection against ischaemia/reperfusion injury in the rat heart 24 hours after administration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Autocrine VEGF signaling is required for vascular homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Diabetic cardiomyopathy revisited
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Mechanisms of adverse effects of anti-VEGF therapy for cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Clinical implications for vascular endothelial growth factor in the lung: friend or foe?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Vascular endothelial growth factor prevents apoptosis and preserves contractile function in hypertrophied infant heart
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Angiogenesis in atherogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Physiologically assessed coronary collateral flow and adverse cardiac ischemic events: a follow-up study in 403 patients with coronary artery disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Hemodynamic changes after levothyroxine treatment in subclinical hypothyroidism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Serum levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea and severe nighttime hypoxia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
The endothelium: dysfunction and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Perfusion-contraction match and mismatch
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Thyroid hormone and the cardiovascular system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Myocardial perfusion by contrast echocardiography: diagnosis of coronary artery disease using contrast-enhanced stress echocardiography and assessment of coronary anatomy and flow reserve
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Acute and chronic effects of airway obstruction on canine left ventricular performance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Stretch-induced VEGF expression in the heart
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
2 November 2018
Quantification of Absolute Myocardial Perfusion in Patients With Coronary Artery Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
30 November 2018
Sunitinib-Induced Systemic Vasoconstriction in Swine Is Endothelin Mediated and Does Not Involve Nitric Oxide or Oxidative Stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
30 November 2018
Reversibility of capillary density after discontinuation of bevacizumab treatment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5988734
retrieved
30 November 2018
The histopathologic evolution of myocardial infarction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myocardial capillary supply is limited in hypertrophic cardiomyopathy: a morphological analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interindividual heterogeneity in the hypoxic regulation of VEGF: significance for the development of the coronary artery collateral circulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The coronary collateral circulation--clinical relevances and therapeutic options
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypothyroidism in patients with renal cell carcinoma: blessing or curse?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flow-mediated, endothelium-dependent vasodilation is impaired in subjects with hypothyroidism, borderline hypothyroidism, and high-normal serum thyrotropin (TSH) values
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Does subclinical hypothyroidism affect cardiac pump performance? Evidence from a magnetic resonance imaging study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thyroid disease and the heart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of thyroid function on blood pressure. Recognition of hypothyroid hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of vascular endothelial growth factor 165 (VEGF165) protects cardiomyocytes against doxorubicin-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiovascular events among 1090 cancer patients treated with sunitinib, interferon, or placebo: A comprehensive adjudicated database analysis demonstrating clinically meaningful reversibility of cardiac events
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41698-018-0056-Z
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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DOI
10.1038/S41698-018-0056-Z
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PMC publication ID
5988734
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PubMed publication ID
30202791
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