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Structural requirements for antiviral activity in nucleosides
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scholarly article
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title
Structural requirements for antiviral activity in nucleosides
(English)
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author
Piet Herdewijn
object named as
Piet Herdewijn
series ordinal
1
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publication date
June 1997
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published in
Drug Discovery Today
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volume
2
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issue
6
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page(s)
235-242
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cites work
The acyclovir legacy: its contribution to antiviral drug discovery
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(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue
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Famciclovir. A review of its pharmacological properties and therapeutic efficacy in herpesvirus infections
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Inhibitory activity of S-adenosylhomocysteine hydrolase inhibitors against human cytomegalovirus replication
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The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro
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Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes
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reference URL
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Synthesis and antiviral activity of the carbocyclic analogues of (E)-5-(2-halovinyl)-2'-deoxyuridines and (E)-5-(2-halovinyl)-2'-deoxycytidines.
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Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine
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reference URL
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Antiviral activities of isometric dideoxynucleosides of D- and L-related stereochemistry
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Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro
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Asymmetric synthesis and biological evaluation of beta-L-(2R,5S)- and alpha-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents
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Inhibition of Epstein-Barr virus replication by a novel L-nucleoside, 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil
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Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.
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Nucleosides with a twist. Can fixed forms of sugar ring pucker influence biological activity in nucleosides and oligonucleotides?
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Understanding the binding of 5-substituted 2'-deoxyuridine substrates to thymidine kinase of herpes simplex virus type-1.
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3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues
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5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile
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Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro
1 reference
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Novel nucleoside strategies for anti-HIV and anti-HSV therapy
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A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells
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Identifiers
DOI
10.1016/S1359-6446(97)01047-7
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