(Q57090919)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372250%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding (English)

1 reference

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4 January 2020

2

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4 January 2020

Dietbert Neumann

10

1 reference

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4 January 2020

Dmitri Svergun

15

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4 January 2020

Uwe Schlattner

16

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4 January 2020

Theo Wallimann

17

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4 January 2020

1

Uwe Riek

1 reference

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4 January 2020

author name string

Peter Konarev

3

1 reference

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4 January 2020

Arne Rufer

4

1 reference

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4 January 2020

Marianne Suter

5

1 reference

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4 January 2020

Alexis Nazabal

6

1 reference

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4 January 2020

Philippe Ringler

7

1 reference

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4 January 2020

Mohamed Chami

8

1 reference

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4 January 2020

Michael Forstner

11

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4 January 2020

Michael Hennig

12

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4 January 2020

Renato Zenobi

13

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4 January 2020

Andreas Engel

14

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4 January 2020

Shirley A Müller

9

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4 January 2020

language of work or name

English

0 references

publication date

27 March 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372250%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 January 2020

published in

1 reference

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4 January 2020

volume

283

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4 January 2020

issue

26

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4 January 2020

page(s)

18331-18343

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

4 January 2020

cites work

1 reference

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

21 January 2018

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AMP-activated protein kinase: balancing the scales.

21 January 2018

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Energy-dependent regulation of cell structure by AMP-activated protein kinase

21 January 2018

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Signaling by AMP-activated Protein Kinase

21 January 2018

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

1 reference

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

21 January 2018

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

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Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

21 January 2018

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Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase

21 January 2018

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The AMP-activated protein kinase--fuel gauge of the mammalian cell?

21 January 2018

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AMP-activated protein kinase--development of the energy sensor concept.

21 January 2018

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Structural basis for AMP binding to mammalian AMP-activated protein kinase

21 January 2018

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AMP-activated protein kinase: the energy charge hypothesis revisited

21 January 2018

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Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

21 January 2018

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AMP-activated protein kinase beta subunit tethers alpha and gamma subunits via its C-terminal sequence (186-270)

21 January 2018

1 reference

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A revised model for AMP-activated protein kinase structure: The alpha-subunit binds to both the beta- and gamma-subunits although there is no direct binding between the beta- and gamma-subunits

21 January 2018

1 reference

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A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias.

21 January 2018

1 reference

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AMPK beta subunit targets metabolic stress sensing to glycogen

21 January 2018

1 reference

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Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization

21 January 2018

1 reference

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AMPK: a key sensor of fuel and energy status in skeletal muscle

21 January 2018

1 reference

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

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Minireview: malonyl CoA, AMP-activated protein kinase, and adiposity

21 January 2018

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New roles for the LKB1-->AMPK pathway.

21 January 2018

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Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer.

21 January 2018

1 reference

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AMP-activated protein kinase protects against anti-epidermal growth factor receptor-Pseudomonas exotoxin A immunotoxin-induced MA11 breast cancer cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Cancer's sweet tooth: the Janus effect of glucose metabolism in tumorigenesis

21 January 2018

1 reference

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AMPK, the metabolic syndrome and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Glycogen storage disease as a unifying mechanism of disease in the PRKAG2 cardiac syndrome

21 January 2018

1 reference

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AMP-activated protein kinase as a drug target.

21 January 2018

1 reference

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Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1.

21 January 2018

1 reference

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Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family.

21 January 2018

1 reference

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Crystallization of the glycogen-binding domain of the AMP-activated protein kinase beta subunit and preliminary X-ray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Co-expression of LKB1, MO25alpha and STRADalpha in bacteria yield the functional and active heterotrimeric complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Structure and mass analysis by scanning transmission electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

EMAN: semiautomated software for high-resolution single-particle reconstructions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Immunoassays with direct mass spectrometric detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

PRIMUS: a Windows PC-based system for small-angle scattering data analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Dual mechanisms regulating AMPK kinase action in the ischemic heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Physiological role of ROCKs in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Posttranslational modifications of the 5'-AMP-activated protein kinase beta1 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

A molecular approach to the concerted action of kinases involved in energy homoeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

Metabolite Channeling: Creatine Kinase Microcompartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708379200

21 January 2018

Identifiers

DOI

10.1074/JBC.M708379200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372250%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference