(Q57131458)

1

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F H Mateus

2

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E J Cesarino

3

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P S Bonato

4

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V L Lanchote

5

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Paula Macedo Cerqueira

1

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Fabiano Henrique Mateus

2

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Evandro José Cesarino

3

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Pierina Sueli Bonato

Journal of Chromatography B: Biomedical Sciences and Applications

4

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language of work or name

English

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publication date

1 December 2000

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January 2000

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published in

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volume

749

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issue

2

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page(s)

153-61

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153-161

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cites work

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Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

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Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19

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Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene

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Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes

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Correlation of polymorphic expression of CYP2D6 mRNA in bladder mucosa and tumor tissue to in vivo debrisoquine hydroxylase activity

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N-Acetylation and hydroxylation polymorphisms in type II diabetics with microvascular disturbances

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Rarity of debrisoquine hydroxylase gene polymorphism in Chinese patients with Parkinson's disease

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Genetic polymorphisms for drug metabolism (CYP2D6) and tardive dyskinesia in schizophrenia

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Polymorphic CYP genes and disease predisposition--what have the studies shown so far?

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Enantioselectivity of 4-hydroxylation in extensive and poor metabolizers of debrisoquine

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