(Q57198378)

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Rearrangement of upstream DH and VH genes to a rearranged immunoglobulin variable region gene inserted into the DQ52-JH region of the immunoglobulin heavy chain locus

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scholarly article

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Rearrangement of upstream DH and VH genes to a rearranged immunoglobulin variable region gene inserted into the DQ52-JH region of the immunoglobulin heavy chain locus (English)

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object named as

Shinsuke Taki

1

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object named as

Klaus Rajewsky

3

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author name string

Frieder Schwenk

2

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language of work or name

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publication date

July 1995

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European Journal of Immunology

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25

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7

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1888-1896

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Molecular analysis of V(D)J recombination

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21 January 2018

Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line

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7 January 2021

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A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

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Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu

1 reference

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7 January 2021

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Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains

1 reference

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7 January 2021

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Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion

1 reference

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7 January 2021

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A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

1 reference

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Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

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An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

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Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Two pairs of recombination signals are sufficient to cause immunoglobulin V-(D)-J joining

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

V(D)J recombination: a functional definition of the joining signals

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel kappa light-chain gene rearrangements in mouse lambda light chain-producing B lymphocytes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

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Excision products of the T cell receptor gene support a progressive rearrangement model of the alpha/delta locus.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

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Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

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A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

VH to VHDJH rearrangement is mediated by the internal VH heptamer

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

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Heavy chain variable (VH) region diversity generated by VH gene replacement in the progeny of a single precursor cell transformed with a temperature-sensitive mutant of Abelson murine leukemia virus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

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Biased usage of two restricted VH gene segments in VH replacement

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Monoclonal anti-allotype antibody towards BALB/c IgM. Analysis of specificity and site of a V-C crossover in recombinant strain BALB-Igh-Va/Igh-Cb

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

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Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Rat anti-T15 monoclonal antibodies with specificity for VH- and VH-VL epitopes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning immunoglobulin variable domains for expression by the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of the B-cell progenitor compartment at the level of single cells.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Extensive splenic B cell activation in IgM-transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective peripheral expansion and activation of B cells expressing endogenous immunoglobulin in mu-transgenic mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunoglobulin heavy chain gene rearrangement involving V-V region recombination

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Conserved patterns of somatic mutation and secondary VH gene rearrangement create aberrant Ig-encoding genes in Epstein-Barr virus-transformed and normal human B lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1 reference

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7 January 2021

based on heuristic

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Cmu gene rearrangement of mouse immunoglobulin genes in normal B cells occurs on both the expressed and nonexpressed chromosomes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Transgenic mice with immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Diversity of germ-line immunoglobulin VH genes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmentally controlled selection of antibody genes: Characterization of individual VH7183 genes and evidence for stage-specific somatic diversification

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

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Antibodies that are specific for a single amino acid interchange in a protein epitope use structurally distinct variable regions

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic basis for expression of the idiotypic network. One unique Ig VH germline gene accounts for the major family of Ab1 and Ab3 (Ab1') antibodies of the GAT system.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Receptor editing in self-reactive bone marrow B cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

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Receptor editing: an approach by autoreactive B cells to escape tolerance

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

B lymphocytes may escape tolerance by revising their antigen receptors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830250715

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EJI.1830250715

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