(Q57719724)

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A mechanistic pharmacokinetic model to assess modified oral drug bioavailability post bariatric surgery in morbidly obese patients: interplay between CYP3A gut wall metabolism, permeability and dissolution

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

A mechanistic pharmacokinetic model to assess modified oral drug bioavailability post bariatric surgery in morbidly obese patients: interplay between CYP3A gut wall metabolism, permeability and dissolution (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

bioavailability

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Darren M. Ashcroft

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

author name string

Devendra Pade

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Masoud Jamei

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Amin Rostami-Hodjegan

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Adam S Darwich

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Basil J Ammori

3

1 reference

Europe PubMed Central

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4 February 2020

publication date

1 July 2012

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Journal of Pharmacy and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

64

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

7

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4 February 2020

1008-1024

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Prevalence and trends in obesity among US adults, 1999-2008

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Bariatric surgery: a review of procedures and outcomes

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Metabolic/bariatric surgery Worldwide 2008.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Vertical gastrectomy for morbid obesity in 216 patients: report of two-year results

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Jejunoileal bypass: a surgery of the past and a review of its complications

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Trends in oral drug bioavailability following bariatric surgery: examining the variable extent of impact on exposure of different drug classes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Population-based mechanistic prediction of oral drug absorption

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Increased gastric pH and the bioavailability of fluconazole and ketoconazole.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Solubility of sparingly-soluble ionizable drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

CYP3A gene expression in human gut epithelium

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Human intestinal glutathione S-transferases

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

The human intestinal cytochrome P450 "pie".

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Quantitative evaluation of the expression and activity of five major sulfotransferases (SULTs) in human tissues: the SULT "pie".

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

The drug efflux-metabolism alliance: biochemical aspects.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: a simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

The effect of rifampin treatment on intestinal expression of human MRP transporters

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

The Simcyp population-based ADME simulator

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Mechanistic approaches to predicting oral drug absorption

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Predicting the impact of physiological and biochemical processes on oral drug bioavailability

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Independent influences of body mass and gastric volumes on satiation in humans.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Laparoscopic gastric bypass, Roux-en-Y- 500 patients: technique and results, with 3-60 month follow-up

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Prospective controlled study of effect of laparoscopic sleeve gastrectomy on small bowel transit time and gastric emptying half-time in morbidly obese patients with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Gastric emptying is not affected by sleeve gastrectomy--scintigraphic evaluation of gastric emptying after sleeve gastrectomy without removal of the gastric antrum

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Changes in the mucosa of the Roux-limb after gastric bypass surgery

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Results of 281 consecutive total laparoscopic Roux-en-Y gastric bypasses to treat morbid obesity

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Significantly altered systemic exposure to atorvastatin acid following gastric bypass surgery in morbidly obese patients.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Roux-en-Y limb motility after total or distal gastrectomy in symptomatic and asymptomatic patients.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Manometric and scintigraphic studies of the relation between motility disturbances in the Roux limb and the Roux-en-Y syndrome.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

New Considerations in Use of Jejunoileal Bypass in Patients with Morbid Obesity

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Roux-en-Y gastric bypass reverses renal glomerular but not tubular abnormalities in excessively obese diabetics

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

The effects of weight loss on renal function in patients with severe obesity

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Effect of drastic weight loss after bariatric surgery on renal parameters in extremely obese patients: long-term follow-up.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Performance of the Cockcroft-Gault, MDRD, and new CKD-EPI formulas in relation to GFR, age, and body size

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Serum protein binding and the role of increased alpha 1-acid glycoprotein in moderately obese male subjects

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Changes in liver histology accompanying massive weight loss after gastroplasty for morbid obesity

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Non-alcoholic steatohepatitis: effect of Roux-en-Y gastric bypass surgery

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Macrophage inhibitory factor, plasminogen activator inhibitor-1, other acute phase proteins, and inflammatory mediators normalize as a result of weight loss in morbidly obese subjects treated with gastric restrictive surgery

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Changes in liver volume from birth to adulthood: a meta-analysis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Prediction of in vivo drug clearance from in vitro data. I: impact of inter-individual variability

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

BDDCS applied to over 900 drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Molecular properties of WHO essential drugs and provisional biopharmaceutical classification

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Pharmacokinetics and bioavailability of fluconazole in patients with AIDS.

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Pharmacokinetics of ciprofloxacin after oral and parenteral administration

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Pharmacokinetic profiles of ciprofloxacin after single intravenous and oral doses

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Inhibition of pentagastrin-stimulated gastric acid secretion by pantoprazole and omeprazole in healthy adults

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.2012.01538.X

21 January 2018

Identifiers

10.1111/J.2042-7158.2012.01538.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22686346%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

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