(Q57798089)

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Microglial calcium release-activated calcium (CRAC) channel inhibition improves outcome from experimental traumatic brain injury and microglia-induced neuronal death

scientific article published on 04 December 2018

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scholarly article

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30 April 2020

Microglial Calcium Release-Activated Calcium Channel Inhibition Improves Outcome from Experimental Traumatic Brain Injury and Microglia-Induced Neuronal Death (English)

1 reference

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30 April 2020

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microglial inhibitor

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Midori A Yenari

7

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30 April 2020

author name string

Atsushi Mizuma

1

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30 April 2020

Jong Youl Kim

2

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30 April 2020

Rachid Kacimi

3

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30 April 2020

Ken Stauderman

4

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30 April 2020

Michael Dunn

5

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30 April 2020

Sudarshan Hebbar

6

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30 April 2020

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publication date

4 December 2018

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30 April 2020

Journal of Neurotrauma

1 reference

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30 April 2020

36

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30 April 2020

996-1007

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30 April 2020

7

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30 April 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6444934/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

FK-506 and cyclosporin A: immunosuppressive mechanism of action and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

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Transcription factors of the NFAT family: regulation and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

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Neurotoxicity of calcineurin inhibitors: impact and clinical management.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

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The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

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Influence of mild hypothermia on inducible nitric oxide synthase expression and reactive nitrogen production in experimental stroke and inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mild hypothermia reduces ICAM-1 expression, neutrophil infiltration and microglia/monocyte accumulation following experimental stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mild hypothermia inhibits inflammation after experimental stroke and brain inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical mechanisms of cyclosporine neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of neuroprotective action of immunosuppressants--facts and hypotheses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple modes of action of tacrolimus (FK506) for neuroprotective action on ischemic damage after transient focal cerebral ischemia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FK506 and a nonimmunosuppressant derivative reduce axonal and myelin damage in experimental autoimmune encephalomyelitis: neuroimmunophilin ligand-mediated neuroprotection in a model of multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic review and metaanalysis of the efficacy of FK506 in experimental stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STIM1, an essential and conserved component of store-operated Ca2+ channel function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of the immunophilin ligand FK506 differentially attenuates neurofilament compaction and impaired axonal transport in injured axons following diffuse traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orai1 is an essential pore subunit of the CRAC channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRACM1 multimers form the ion-selective pore of the CRAC channel.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: comparison with tissue plasminogen activator.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of the CRAC channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal cell apoptosis induced by nephrotoxic drugs: cellular and molecular mechanisms and potential approaches to modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide-induced down-regulation of Ca2+ release-activated Ca2+ currents (I CRAC) but not Ca2+-activated TRPM4-like currents (I CAN) in cultured mouse microglial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ca2+ release-activated Ca2+ current (I(CRAC)) mediates store-operated Ca2+ entry in rat microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Digitally quantifying cerebral hemorrhage using Photoshop and Image J.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporine-A as a neuroprotective agent against stroke: its translation from laboratory research to clinical application.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunology of stroke: from mechanisms to translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor NF-κB regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressant FK506: focusing on neuroprotective effects following brain and spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre- and post-treatment with cyclosporine A in a rat model of transient focal cerebral ischaemia with multimodal MRI screening.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothermia and pharmacological regimens that prevent overexpression and overactivity of the extracellular calcium-sensing receptor protect neurons against traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin and glial signaling: neuroinflammation and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional mechanisms of CRAC channel regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockdown of STIM1 improves neuronal survival after traumatic neuronal injury through regulating mGluR1-dependent Ca(2+) signaling in mouse cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological induction of the 70-kDa heat shock protein protects against brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of phagocytosis and cytokine secretion by store-operated calcium entry in primary isolated murine microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and neuroprotection in traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in gliovascular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporine in acute ischemic stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STIM and ORAI proteins in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of STIM2 improves neuronal survival after traumatic brain injury by alleviating calcium overload and mitochondrial dysfunction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The safety of calcineurin inhibitors for kidney-transplant patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Store-Operated Calcium Channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammation in animal models of traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/30351197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/NEU.2018.5856

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30351197%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30351197%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30351197%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

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