(Q35748218)

PubMed publication ID

10 August 2017

1 reference

title

Molecular mechanisms of neuroprotective action of immunosuppressants--facts and hypotheses (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

12 May 2020

1 reference

1 reference

Bożena Kamińska-Kaczmarek

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

12 May 2020

Malgorzata Zawadzka

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

Katarzyna Gawęda-Walerych

12 May 2020

series ordinal

2

object named as

Katarzyna Gaweda-Walerych

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

12 May 2020

publication date

1 January 2004

1 reference

PubMed publication ID

15090260

Journal of Cellular and Molecular Medicine

10 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

12 May 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

12 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

12 May 2020

page(s)

45-58

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

12 May 2020

cites work

1 reference

12 December 2020

An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury

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12 December 2020

Brain-derived neurotrophic factor prevents neuronal death and glial activation after global ischemia in the rat.

1 reference

12 December 2020

CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons

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12 December 2020

Roles of nitric oxide in brain hypoxia-ischemia

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12 December 2020

Neuroprotective FK506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats

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12 December 2020

Postinjury cyclosporin A administration limits axonal damage and disconnection in traumatic brain injury

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12 December 2020

The mitochondrial permeability transition pore and its role in cell death

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12 December 2020

Pathobiology of ischaemic stroke: an integrated view

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12 December 2020

Cyclosporin A regulates the levels of cyclophilin A in neuroblastoma cells in culture

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12 December 2020

Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons

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12 December 2020

Evidence for neuroprotective effects of endogenous brain-derived neurotrophic factor after global forebrain ischemia in rats

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12 December 2020

High level calcineurin activity predisposes neuronal cells to apoptosis

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12 December 2020

Potential mechanisms of interleukin-1 involvement in cerebral ischaemia.

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12 December 2020

Expression of IL-6 in the ischemic penumbra

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12 December 2020

Attenuation and augmentation of ischaemia-related neuronal death by tumour necrosis factor-alpha in vitro

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12 December 2020

Interleukin 1 in the brain: biology, pathology and therapeutic target

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12 December 2020

Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys

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12 December 2020

Cyclosporin A-sensitive signaling pathway involving calcineurin regulates survival of reactive astrocytes

1 reference

12 December 2020

Cyclosporin A, but not FK506, prevents the downregulation of phosphorylated Akt after transient focal ischemia in the rat.

1 reference

12 December 2020

The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury

1 reference

12 December 2020

Neuroimmunophilins: novel neuroprotective and neuroregenerative targets

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12 December 2020

Role of IL-1alpha and IL-1beta in ischemic brain damage.

1 reference

12 December 2020

Involvement of the brain-derived neurotrophic factor/TrkB pathway in neuroprotecive effect of cyclosporin A in forebrain ischemia

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12 December 2020

Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity.

1 reference

12 December 2020

The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis

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12 December 2020

Neuroprotective effect of immunosuppressant FK506 in transient focal ischemia in rat: therapeutic time window for FK506 in transient focal ischemia

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12 December 2020

FK506 attenuates early ischemic neuronal death in a monkey model of stroke

1 reference

12 December 2020

Calcineurin as a multifunctional regulator

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12 December 2020

Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811.

1 reference

12 December 2020

Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization

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12 December 2020

Cyclophilin-mediated pathways in the effect of cyclosporin A on endothelial cells: role of vascular endothelial growth factor

1 reference

12 December 2020

Cyclosporin A blocks muscle differentiation by inducing oxidative stress and inhibiting the peptidyl-prolyl-cis-trans isomerase activity of cyclophilin A: cyclophilin A protects myoblasts from cyclosporin A-induced cytotoxicity

1 reference

12 December 2020

Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition

1 reference

12 December 2020

A combined treatment with tacrolimus (FK506) and recombinant tissue plasminogen activator for thrombotic focal cerebral ischemia in rats: increased neuroprotective efficacy and extended therapeutic time window

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12 December 2020

FK506 treatment inhibits caspase-3 activation and promotes oligodendroglial survival following traumatic spinal cord injury

1 reference

12 December 2020

Restricted clinical efficacy of cyclosporin A on rat transient middle cerebral artery occlusion

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12 December 2020

The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys

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12 December 2020

FK506 is neuroprotective in a model of antiretroviral toxic neuropathy.

1 reference

12 December 2020

Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: dose dependency, therapeutic time window and long-term efficacy

1 reference

12 December 2020

Immunosuppressant FK506 affects multiple signaling pathways and modulates gene expression in astrocytes

1 reference

12 December 2020

Differential effects of immunophilin-ligands (FK506 and V-10,367) on survival and regeneration of rat retinal ganglion cells in vitro and after optic nerve crush in vivo

1 reference

12 December 2020

Changes in peptidyl-prolyl cis/trans isomerase activity and FK506 binding protein expression following neuroprotection by FK506 in the ischemic rat brain

1 reference

12 December 2020

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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12 December 2020

High brain densities of the immunophilin FKBP colocalized with calcineurin

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12 December 2020

Cyclosporin A protects against ischemia-reperfusion injury in the brain

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12 December 2020

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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12 December 2020

Upregulation of bax protein levels in neurons following cerebral ischemia.

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12 December 2020

The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve

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12 December 2020

Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia

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12 December 2020

Calcineurin-mediated protein dephosphorylation in brain nerve terminals regulates the release of glutamate

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12 December 2020

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

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12 December 2020

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

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12 December 2020

Dual role of nitric oxide in focal cerebral ischemia

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12 December 2020

Presynaptic modulation of cortical synaptic activity by calcineurin.

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12 December 2020

A Role for Calcineurin (Protein Phosphatase-2B) in the Regulation of Glutamate Release

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12 December 2020

Immunophilins and nervous system

1 reference

12 December 2020

Calcineurin functions in Ca(2+)-activated cell death in mammalian cells

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12 December 2020

Distribution and activity of calcineurin in rat tissues. Evidence for post-transcriptional regulation of testis-specific calcineurin B.

1 reference

12 December 2020

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity

1 reference

12 December 2020

The therapeutic window in ischemic brain injury

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12 December 2020

Viability thresholds and the penumbra of focal ischemia

1 reference

12 December 2020

DNA damage consistent with apoptosis in transient focal ischaemic neocortex.

1 reference

12 December 2020

Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus

1 reference

12 December 2020

Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

1 reference

12 December 2020

Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia

1 reference

12 December 2020

Characterization of microglial reaction after middle cerebral artery occlusion in rat brain

1 reference

12 December 2020

Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis.

1 reference

12 December 2020

Increased expression of TGF-beta 1 in brain tissue after ischemic stroke in humans

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12 December 2020

Neuroprotective effect of FK506, an immunosuppressant, on transient global ischemia in gerbil.

1 reference

12 December 2020

Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

1 reference

12 December 2020

Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils

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12 December 2020

CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression

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12 December 2020

Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats

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12 December 2020

Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A

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12 December 2020

Duration of glutamate release after acute ischemic stroke

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12 December 2020

Calcineurin inhibitor, FK506, prevents reduction in the binding capacity of cyclic AMP-dependent protein kinase in ischemic gerbil brain

1 reference

12 December 2020

Transcription factors of the NFAT family: regulation and function

1 reference

12 December 2020

Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription

1 reference

12 December 2020

Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury

1 reference

12 December 2020

Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism.

1 reference

12 December 2020

CREB: a major mediator of neuronal neurotrophin responses

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12 December 2020

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice

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12 December 2020

Apoptosis, excitotoxicity, and neuropathology

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12 December 2020

NGF delays rather than prevents the cholinergic terminal damage and delayed neuronal death in the hippocampus after ischemia

1 reference

12 December 2020

Dose-dependent, protective effect of FK506 against white matter changes in the rat brain after chronic cerebral ischemia

1 reference

12 December 2020

Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

1 reference

12 December 2020

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.

1 reference

12 December 2020

Annual review prize lecture cytokines - killers in the brain?

1 reference

12 December 2020

Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats

1 reference

12 December 2020

Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury.

1 reference

12 December 2020

Expression of nitric oxide synthase-2 in glia associated with CNS pathology.

1 reference

12 December 2020

10.1111/J.1582-4934.2004.TB00259.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740149&resulttype=core&format=json

12 May 2020

PubMed publication ID

15090260

1 reference