(Q44554996)

English

Changes in peptidyl-prolyl cis/trans isomerase activity and FK506 binding protein expression following neuroprotection by FK506 in the ischemic rat brain

scientific article published in January 2003

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scholarly article

1 reference

Europe PubMed Central

4 December 2017

Changes in peptidyl-prolyl cis/trans isomerase activity and FK506 binding protein expression following neuroprotection by FK506 in the ischemic rat brain (English)

1 reference

Europe PubMed Central

4 December 2017

author name string

Brecht S

1

1 reference

Europe PubMed Central

4 December 2017

Schwarze K

2

1 reference

Europe PubMed Central

4 December 2017

Waetzig V

3

1 reference

Europe PubMed Central

4 December 2017

Christner C

4

1 reference

Europe PubMed Central

4 December 2017

Heiland S

5

1 reference

Europe PubMed Central

4 December 2017

Fischer G

6

1 reference

Europe PubMed Central

4 December 2017

Sartor K

7

1 reference

Europe PubMed Central

4 December 2017

Herdegen T

8

1 reference

Europe PubMed Central

4 December 2017

language of work or name

0 references

publication date

1 January 2003

1 reference

Europe PubMed Central

4 December 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

4 December 2017

120

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Europe PubMed Central

4 December 2017

4

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Europe PubMed Central

4 December 2017

1037-1048

1 reference

Europe PubMed Central

4 December 2017

Post-ischemic alterations in [3H]FK506 binding in the gerbil and rat brains.

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FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier.

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Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

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Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

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Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65)

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FK506 accelerates functional recovery following nerve grafting in a rat model

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The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain.

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Early and delayed neuroprotective effects of FK506 on experimental focal ischemia quantitatively assessed by diffusion-weighted MRI.

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Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

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Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

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FK506 and the role of immunophilins in nerve regeneration

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FK506 and the role of the immunophilin FKBP-52 in nerve regeneration

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The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve

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A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

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Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.

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Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV irradiation.

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An immunosuppressant, FK506, protects hippocampal neurons from forebrain ischemia in the mongolian gerbil.

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A Protease-Free Assay for Peptidyl Prolylcis/transIsomerases Using Standard Peptide Substrates

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c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

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Postischemic changes in the immunophilin FKBP12 in the rat brain.

1 reference

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7 January 2021

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Structure-function relationships in the FK506-binding protein (FKBP) family of peptidylprolyl cis-trans isomerases

1 reference

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7 January 2021

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The neuroprotective actions of FK506 binding protein ligands: neuronal survival is triggered by de novo RNA synthesis, but is independent of inhibition of JNK and calcineurin.

1 reference

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FK506 promotes functional recovery in crushed rat sciatic nerve

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Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

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Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia

1 reference

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7 January 2021

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Neuronal regeneration enhances the expression of the immunophilin FKBP-12

1 reference

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Rapid and long-lasting suppression of the ATF-2 transcription factor is a common response to neuronal injury

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Two distinct action mechanisms of immunophilin-ligand complexes for the blockade of T-cell activation

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Activity and expression of JNK1, p38 and ERK kinases, c-Jun N-terminal phosphorylation, and c-jun promoter binding in the adult rat brain following kainate-induced seizures

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Potential role of calcineurin for brain ischemia and traumatic injury

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Binding capacity of FK506 binding protein after 2-hour hemispheric ischemia in gerbil brain.

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Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice

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Neural roles of immunophilins and their ligands

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Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

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Tacrolimus (FK506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats.

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Immunophilins in the nervous system

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FK 506 for liver, kidney, and pancreas transplantation

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High brain densities of the immunophilin FKBP colocalized with calcineurin

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TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins.

1 reference

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Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

1 reference

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Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

1 reference

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Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

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based on heuristic

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The immunophilin ligand FK506, but not GPI-1046, protects against neuronal death and inhibits c-Jun expression in the substantia nigra pars compacta following transection of the rat medial forebrain bundle

1 reference

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based on heuristic

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FK506 antagonizes apoptosis and c-jun protein expression in neuronal cultures

1 reference

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Chicken FK506-binding protein, FKBP65, a member of the FKBP family of peptidylprolyl cis-trans isomerases, is only partially inhibited by FK506.

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Identifiers

10.1016/S0306-4522(03)00404-4

1 reference

Europe PubMed Central

4 December 2017

1 reference

Europe PubMed Central

4 December 2017

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