(Q57858865)

The highways and byways of mRNA decay

31 March 2020

1 reference

Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function

31 March 2020

1 reference

Cutting the nonsense: the degradation of PTC-containing mRNAs

31 March 2020

1 reference

Execution of nonsense-mediated mRNA decay: what defines a substrate?

31 March 2020

1 reference

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

31 March 2020

1 reference

An mRNA surveillance mechanism that eliminates transcripts lacking termination codons

31 March 2020

1 reference

Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA

31 March 2020

1 reference

Exosome-mediated recognition and degradation of mRNAs lacking a termination codon

31 March 2020

1 reference

Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation

31 March 2020

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A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay

31 March 2020

1 reference

A late-acting quality control process for mature eukaryotic rRNAs

31 March 2020

1 reference

Immature small ribosomal subunits can engage in translation initiation in Saccharomyces cerevisiae

31 March 2020

1 reference

In vitro reconstitution of eukaryotic translation reveals cooperativity between release factors eRF1 and eRF3

31 March 2020

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A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor

31 March 2020

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Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors, eRF1 and eRF3.

31 March 2020

1 reference

Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes

31 March 2020

1 reference

Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop-off to initiate no-go decay

31 March 2020

1 reference

Kinetic analysis reveals the ordered coupling of translation termination and ribosome recycling in yeast

31 March 2020

1 reference

The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis

31 March 2020

1 reference

Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1.

31 March 2020

1 reference

Yeast CBP1 mRNA 3' end formation is regulated during the induction of mitochondrial function

31 March 2020

1 reference

An intronic polyadenylation site in human and mouse CstF-77 genes suggests an evolutionarily conserved regulatory mechanism

31 March 2020

1 reference

Regulation of poly(A) site choice of several yeast mRNAs

31 March 2020

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A single subunit, Dis3, is essentially responsible for yeast exosome core activity

31 March 2020

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Endonucleolytic RNA cleavage by a eukaryotic exosome

31 March 2020

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The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

31 March 2020

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Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs

31 March 2020

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The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

31 March 2020

1 reference

The GPR54 gene as a regulator of puberty

31 March 2020

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A germline mutation abolishing the original stop codon of the human adenine phosphoribosyltransferase (APRT) gene leads to complete loss of the enzyme protein

31 March 2020

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Polypyrimidine tract binding protein prevents activity of an intronic regulatory element that promotes usage of a composite 3'-terminal exon

31 March 2020

1 reference

Yeast pheromone receptor genes STE2 and STE3 are differently regulated at the transcription and polyadenylation level

31 March 2020

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Cryptic polyadenylation sites within the coding sequence of three yeast genes expressed in tobacco

31 March 2020

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U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation

31 March 2020

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SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

31 March 2020

1 reference

Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila

31 March 2020

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Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decay

31 March 2020

1 reference

Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

31 March 2020

1 reference

Cytoplasmic decay of intergenic transcripts in Saccharomyces cerevisiae

31 March 2020

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Nascent peptide-dependent translation arrest leads to Not4p-mediated protein degradation by the proteasome

31 March 2020

1 reference

Translation of aberrant mRNAs lacking a termination codon or with a shortened 3'-UTR is repressed after initiation in yeast

31 March 2020

1 reference

Translation of the poly(A) tail plays crucial roles in nonstop mRNA surveillance via translation repression and protein destabilization by proteasome in yeast

31 March 2020

1 reference

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

31 March 2020

1 reference

A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism

31 March 2020

1 reference

Dom34:hbs1 plays a general role in quality-control systems by dissociation of a stalled ribosome at the 3' end of aberrant mRNA.

31 March 2020

1 reference

Analysis of Dom34 and its function in no-go decay

31 March 2020

1 reference

Receptor for activated C kinase 1 stimulates nascent polypeptide-dependent translation arrest

31 March 2020

1 reference

Mapping the electrostatic potential within the ribosomal exit tunnel

31 March 2020

1 reference

The structure of the eukaryotic ribosome at 3.0 Å resolution

31 March 2020

1 reference

Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex

31 March 2020

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The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex

31 March 2020

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Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression.

31 March 2020

1 reference

RNA under attack: cellular handling of RNA damage

31 March 2020

1 reference

Depurination of Brome mosaic virus RNA3 in vivo results in translation-dependent accelerated degradation of the viral RNA.

31 March 2020

1 reference

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

31 March 2020

1 reference

Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast

31 March 2020

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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

31 March 2020

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Identification of functional, endogenous programmed -1 ribosomal frameshift signals in the genome of Saccharomyces cerevisiae

31 March 2020

1 reference

Endogenous ribosomal frameshift signals operate as mRNA destabilizing elements through at least two molecular pathways in yeast

31 March 2020

1 reference

Nascent peptide-mediated translation elongation arrest coupled with mRNA degradation in the CGS1 gene of Arabidopsis

31 March 2020

1 reference

Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits

31 March 2020

1 reference

Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates

31 March 2020

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A translation-like cycle is a quality control checkpoint for maturing 40S ribosome subunits

31 March 2020

1 reference

rRNA maturation as a "quality" control step in ribosomal subunit assembly in Dictyostelium discoideum

31 March 2020

1 reference

Evolution of nonstop, no-go and nonsense-mediated mRNA decay and their termination factor-derived components

31 March 2020

1 reference

Why Dom34 stimulates growth of cells with defects of 40S ribosomal subunit biosynthesis.

31 March 2020

1 reference

Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways

31 March 2020

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Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression

31 March 2020

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Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton

31 March 2020

1 reference

Structure of yeast Dom34: a protein related to translation termination factor Erf1 and involved in No-Go decay

31 March 2020

1 reference

Structural and functional insights into Dom34, a key component of no-go mRNA decay

31 March 2020

1 reference

Eukaryotic Lsm proteins: lessons from bacteria

31 March 2020

1 reference

Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome

31 March 2020

1 reference

Structure of the Dom34-Hbs1 complex and implications for no-go decay

31 March 2020

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The product of the mammalian orthologue of the Saccharomyces cerevisiae HBS1 gene is phylogenetically related to eukaryotic release factor 3 (eRF3) but does not carry eRF3-like activity

31 March 2020

1 reference

Omnipotent role of archaeal elongation factor 1 alpha (EF1 ) in translational elongation and termination, and quality control of protein synthesis

31 March 2020

1 reference

Novel G-protein complex whose requirement is linked to the translational status of the cell.

31 March 2020

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Conserved functions of yeast genes support the duplication, degeneration and complementation model for gene duplication

31 March 2020

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The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L

31 March 2020

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The translation machinery and 70 kd heat shock protein cooperate in protein synthesis

31 March 2020

1 reference

Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex

31 March 2020

1 reference

Structural insights into eRF3 and stop codon recognition by eRF1

31 March 2020

1 reference

Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

31 March 2020

1 reference

The iron-sulphur protein RNase L inhibitor functions in translation termination

31 March 2020

1 reference

The role of ABCE1 in eukaryotic posttermination ribosomal recycling

31 March 2020

1 reference

The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

31 March 2020

1 reference

Structural basis of highly conserved ribosome recycling in eukaryotes and archaea

31 March 2020

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Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome

31 March 2020

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Biology of trans-translation

31 March 2020

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The bacterial toxin RelE induces specific mRNA cleavage in the A site of the eukaryote ribosome

31 March 2020

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Cleavage of the A site mRNA codon during ribosome pausing provides a mechanism for translational quality control

31 March 2020

1 reference

The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE

31 March 2020

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Ribosome stalling during translation elongation induces cleavage of mRNA being translated in Escherichia coli

31 March 2020

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SmpB as the handyman of tmRNA during trans-translation

31 March 2020

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Decoding in the Absence of a Codon by tmRNA and SmpB in the Ribosome

31 March 2020

1 reference

Beyond ribosome rescue: tmRNA and co-translational processes

31 March 2020

1 reference

The post-transcriptional steps of eukaryotic ribosome biogenesis

31 March 2020

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Powering through ribosome assembly

31 March 2020

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RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

31 March 2020

1 reference

A 'garbage can' for ribosomes: how eukaryotes degrade their ribosomes

31 March 2020

1 reference

A role for ubiquitin in the clearance of nonfunctional rRNAs

31 March 2020

1 reference

40S subunit dissociation and proteasome-dependent RNA degradation in nonfunctional 25S rRNA decay

31 March 2020

1 reference

NMD: a multifaceted response to premature translational termination

31 March 2020

1 reference

12 December 2020

Yeast dom34 mutants are defective in multiple developmental pathways and exhibit decreased levels of polyribosomes

1 reference

12 December 2020

Eukaryotic polypeptide chain release factor eRF3 is an eRF1- and ribosome-dependent guanosine triphosphatase

1 reference

12 December 2020

The pelota locus encodes a protein required for meiotic cell division: an analysis of G2/M arrest in Drosophila spermatogenesis

1 reference

12 December 2020