(Q57904558)

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Fewer bone disease events, improvement in bone remodeling, and evidence of bone healing with bortezomib plus melphalan-prednisone vs. melphalan-prednisone in the phase III VISTA trial in multiple myeloma

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24 January 2020

Fewer bone disease events, improvement in bone remodeling, and evidence of bone healing with bortezomib plus melphalan-prednisone vs. melphalan-prednisone in the phase III VISTA trial in multiple myeloma (English)

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24 January 2020

phase III clinical trial

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based on heuristic

inferred from title

multiple myeloma

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based on heuristic

inferred from title

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based on heuristic

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Athanasios Dimopoulos

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24 January 2020

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24 January 2020

Jesús San Miguel

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24 January 2020

Paul G. Richardson

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24 January 2020

Hartmut Goldschmidt

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24 January 2020

Evangelos Terpos

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24 January 2020

Michel Delforge

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24 January 2020

Nuriet K Khuageva

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24 January 2020

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24 January 2020

Maria Teresa Petrucci

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24 January 2020

William Deraedt

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24 January 2020

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Andrew Cakana

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24 January 2020

Helgi van de Velde

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24 January 2020

Hila Magen-Nativ

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24 January 2020

María Victoria Mateos

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24 January 2020

Dixie-Lee Esseltine

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24 January 2020

Deborah J Eaves

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24 January 2020

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Rudolf Schlag

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24 January 2020

Martin Kropff

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24 January 2020

Kevin Liu

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24 January 2020

Olga S Samoilova

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24 January 2020

publication date

30 March 2011

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24 January 2020

European Journal of Haematology

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24 January 2020

86

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24 January 2020

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24 January 2020

372-384

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24 January 2020

The use of bisphosphonates in multiple myeloma: recommendations of an expert panel on behalf of the European Myeloma Network

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Review of 1027 patients with newly diagnosed multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

International uniform response criteria for multiple myeloma.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Pathogenesis of myeloma bone disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Myeloma cell-induced disruption of bone remodelling compartments leads to osteolytic lesions and generation of osteoclast-myeloma hybrid cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Pulse treatment with the proteasome inhibitor bortezomib inhibits osteoclast resorptive activity in clinically relevant conditions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

The histone deacetylase inhibitor, PXD101, potentiates bortezomib-induced anti-multiple myeloma effect by induction of oxidative stress and DNA damage

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib inhibits maturation and function of osteoclasts from PBMCs of patients with multiple myeloma by downregulating TRAF6.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib inhibits human osteoclastogenesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib in combination with conventional chemotherapeutic agents for multiple myeloma compared with bortezomib alone

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib reduces serum dickkopf-1 and receptor activator of nuclear factor-?B ligand concentrations and normalises indices of bone remodelling in patients with relapsed multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib inhibits osteoclast activity in patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

First-line treatment with bortezomib rapidly stimulates both osteoblast activity and bone matrix deposition in patients with multiple myeloma, and stimulates osteoblast proliferation and differentiation in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Stimulation of new bone formation by the proteasome inhibitor, bortezomib: implications for myeloma bone disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Therapy with bortezomib plus dexamethasone induces osteoblast activation in responsive patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib induces osteoblast differentiation via Wnt-independent activation of beta-catenin/TCF signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Increased bone mineral density in a subset of patients with relapsed multiple myeloma who received the combination of bortezomib, dexamethasone and zoledronic acid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib alone or in combination with the histone deacetylase inhibitor JNJ-26481585: effect on myeloma bone disease in the 5T2MM murine model of myeloma.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Bortezomib plus melphalan and prednisone compared with melphalan and prednisone in previously untreated multiple myeloma: updated follow-up and impact of subsequent therapy in the phase III VISTA trial

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

American Society of Clinical Oncology clinical practice guidelines: the role of bisphosphonates in multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

High serum bone-specific alkaline phosphatase level after bortezomib-combined therapy in refractory multiple myeloma: possible role of bortezomib on osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

A prospective evaluation of the biochemical, metabolic, hormonal and structural bone changes associated with bortezomib response in multiple myeloma patients

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Serum concentrations of DKK-1 correlate with the extent of bone disease in patients with multiple myeloma.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Dickkopf-1: a suitable target for the management of myeloma bone disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Serum concentrations of Dickkopf-1 protein are increased in patients with multiple myeloma and reduced after autologous stem cell transplantation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

DKK1 correlates with response and predicts rapid relapse after autologous stem cell transplantation in multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Glucocorticoid suppresses the canonical Wnt signal in cultured human osteoblasts.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0609.2011.01599.X

21 January 2018

Identifiers

10.1111/J.1600-0609.2011.01599.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21366694%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21366694%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

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