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Chapter 1 Transcription factor genes in type 2 diabetes
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title
Chapter 1 Transcription factor genes in type 2 diabetes
(English)
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main subject
type 2 diabetes
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author
Michael N Weedon
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object named as
Michael N. Weedon
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Andrew Tym Hattersley
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object named as
Andrew T. Hattersley
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Tim Frayling
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object named as
Timothy M. Frayling
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publication date
2006
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page(s)
1-14
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cites work
The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism
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The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits
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Phenotypic consequences of the peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism: the weight of the evidence in genetic association studies
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Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
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Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization
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Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension
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Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma
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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
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The future of genetic studies of complex human diseases
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Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis
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Linkage of type 2 diabetes to the glucokinase gene
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Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus
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Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus
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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
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Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)
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Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY.
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Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
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Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus
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Genetic cause of hyperglycaemia and response to treatment in diabetes
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The genetics of type 2 diabetes
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Genetics of type 1 diabetes mellitus
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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
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Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility
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Growing evidence for diabetes susceptibility genes from genome scan data
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A genetic switch in pancreatic beta-cells: implications for differentiation and haploinsufficiency.
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beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors
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Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families
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Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2.
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Genes, environment and Oji-Cree type 2 diabetes
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Glomerulocystic kidney disease in an adult presenting as end-stage renal failure
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Messenger RNA transcripts of the hepatocyte nuclear factor-1alpha gene containing premature termination codons are subject to nonsense-mediated decay
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HNF-1alpha G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community
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Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM.
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The Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: evidence from studies of 231 glucose-tolerant first degree relativ
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Variants in the hepatocyte nuclear factor-1alpha and -4alpha genes in Finnish and Chinese subjects with late-onset type 2 diabetes.
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Hepatocyte nuclear factor 1alpha coding mutations are an uncommon contributor to early-onset type 2 diabetes in Ashkenazi Jews
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Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians
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The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients
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Transcription factor 1 and beta-cell function in glucose-tolerant subjects.
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Comparison of the impact of the I27L polymorphism of the hepatocyte nuclear factor-1alpha on estimated and measured beta cell indices
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Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
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A comprehensive review of genetic association studies
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Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs
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Searching for Type 2 Diabetes Genes on Chromosome 20
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A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young
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Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function
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Rare variants identified in the HNF-4α β-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes
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Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes
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A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.
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Common Variants of the Hepatocyte Nuclear Factor-4 P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population
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The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells
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Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells
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Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
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Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes
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Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus
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Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations
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IPF-1 gene variation and the development of type 2 diabetes
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https://api.crossref.org/works/10.1016%2FS1569-2566%2806%2905001-0
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Mutations in the insulin promoter factor-1 gene in late-onset type 2 diabetes mellitus
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1569-2566%2806%2905001-0
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7 January 2021
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Missense mutations in the human insulin promoter factor-1 gene and their relation to maturity-onset diabetes of the young and late-onset type 2 diabetes mellitus in caucasians
1 reference
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Association of polymorphism in the NeuroD/BETA2 gene with type 1 diabetes in the Japanese
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The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 1 diabetes mellitus in caucasians
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NeuroD/beta2 gene G-->A polymorphism may affect onset pattern of type 1 diabetes in Japanese
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NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epide
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Lack of association of the Ala45Thr variant in the BETA2/NEUROD1 with type 1 diabetes in Japanese
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Lack of association of the Ala(45)Thr polymorphism and other common variants of the NeuroD gene with type 1 diabetes
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The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 2 diabetes mellitus in a Polish population
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Studies of the variability of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2) and the dimerization cofactor of HNF-1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function
1 reference
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Hepatocyte nuclear factor-1alpha gene and non-insulin-dependent diabetes mellitus in the Japanese population
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10.1016/S1569-2566(06)05001-0
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