(Q58024148)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

An investigation of the ligand binding properties and negative cooperativity of soluble insulin-like growth factor receptors (English)

1 reference

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29 December 2019

1 reference

1 reference

2

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29 December 2019

author name string

Katharina Helen Surinya

1

1 reference

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29 December 2019

Filomena Occhiodoro

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Geoffrey Leonard Francis

5

1 reference

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29 December 2019

Kenneth Siddle

6

1 reference

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29 December 2019

Grant W Booker

4

1 reference

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29 December 2019

John C Wallace

7

1 reference

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29 December 2019

Leah J Cosgrove

8

1 reference

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29 December 2019

language of work or name

English

0 references

publication date

3 December 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056713%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

29 December 2019

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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29 December 2019

volume

283

1 reference

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29 December 2019

issue

9

1 reference

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29 December 2019

page(s)

5355-5363

1 reference

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A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.

29 December 2019

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The role of the IGF system in cancer growth and metastasis: overview and recent insights

21 January 2018

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Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

21 January 2018

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Insulin-like growth factor expression in human cancer cell lines

21 January 2018

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Elevated serum insulin-like growth factor (IGF)-II and IGF binding protein-2 in patients with colorectal cancer

21 January 2018

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Molecular interactions of the IGF system

21 January 2018

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Homozygous and heterozygous expression of a novel insulin-like growth factor-I mutation

21 January 2018

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Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and development

21 January 2018

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Structure and function of the type 1 insulin-like growth factor receptor.

21 January 2018

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Interaction of the .alpha..beta. dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation

21 January 2018

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Transmembrane domain interactions are necessary for negative cooperativity of the insulin receptor

21 January 2018

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Dimeric fragment of the insulin receptor alpha-subunit binds insulin with full holoreceptor affinity.

21 January 2018

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Role of insulin receptor dimerization domains in ligand binding, cooperativity, and modulation by anti-receptor antibodies

21 January 2018

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Fusion of insulin receptor ectodomains to immunoglobulin constant domains reproduces high-affinity insulin binding in vitro

21 January 2018

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High affinity insulin binding by soluble insulin receptor extracellular domain fused to a leucine zipper

21 January 2018

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Characterization of ligand binding of a soluble human insulin-like growth factor I receptor variant suggests a ligand-induced conformational change

21 January 2018

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Mapping of an NH2-terminal ligand binding site of the insulin receptor by alanine scanning mutagenesis

21 January 2018

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Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand binding

21 January 2018

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Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor.

21 January 2018

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Rescue of ligand binding of a mutant IGF-I receptor by complementation

21 January 2018

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Complementation analysis demonstrates that insulin cross-links both alpha subunits in a truncated insulin receptor dimer

21 January 2018

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Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation

21 January 2018

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A region of the insulin receptor important for ligand binding (residues 450-601) is recognized by patients' autoimmune antibodies and inhibitory monoclonal antibodies

21 January 2018

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Structure of the insulin receptor ectodomain reveals a folded-over conformation

21 January 2018

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The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling.

21 January 2018

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Structural biology of insulin and IGF1 receptors: implications for drug design

21 January 2018

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Insulin and its receptor: structure, function and evolution

21 January 2018

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The insulin-like growth factor-I receptor. Structure, ligand-binding mechanism and signal transduction.

21 January 2018

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Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR.

21 January 2018

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Production and characterization of recombinant insulin-like growth factor-I (IGF-I) and potent analogues of IGF-I, with Gly or Arg substituted for Glu 3, following their expression in Escherichia coli as fusion proteins

21 January 2018

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Insulin-like growth factor (IGF)-II binding to IGF-binding proteins and IGF receptors is modified by deletion of the N-terminal hexapeptide or substitution of arginine for glutamate-6 in IGF-II.

21 January 2018

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Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis

21 January 2018

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Precise mapping of an IGF-I-binding site on the IGF-1R.

21 January 2018

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Negative cooperativity in the insulin-like growth factor-I receptor and a chimeric IGF-I/insulin receptor

21 January 2018

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Binding properties of chimeric insulin receptors containing the cysteine-rich domain of either the insulin-like growth factor I receptor or the insulin receptor related receptor

21 January 2018

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Changing the insulin receptor to possess insulin-like growth factor I ligand specificity

21 January 2018

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The ligand specificities of the insulin receptor and the insulin-like growth factor I receptor reside in different regions of a common binding site

21 January 2018

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The insulin and EGF receptor structures: new insights into ligand-induced receptor activation.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M707054200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference