(Q58228866)

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Sperm Motility Is Lost In Vitro as a Consequence of Mitochondrial Free Radical Production and the Generation of Electrophilic Aldehydes but Can Be Significantly Rescued by the Presence of Nucleophilic Thiols1

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12 February 2020

Sperm motility is lost in vitro as a consequence of mitochondrial free radical production and the generation of electrophilic aldehydes but can be significantly rescued by the presence of nucleophilic thiols (English)

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12 February 2020

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12 February 2020

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12 February 2020

Geoffry N De Iuliis

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12 February 2020

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Lisa A Mitchell

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12 February 2020

Sarah R Lambourne

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12 February 2020

Haley S Connaughton

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12 February 2020

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Biology of Reproduction

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8 November 2012

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12 February 2020

Biology of Reproduction

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12 February 2020

87

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12 February 2020

5

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12 February 2020

110

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12 February 2020

Redox regulation of human sperm function: from the physiological control of sperm capacitation to the etiology of infertility and DNA damage in the germ line

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Quantitative analysis of gene-specific DNA damage in human spermatozoa.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Antioxidant strategies in the epididymis.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

DNA fragmentation of spermatozoa and assisted reproduction technology

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Sulfhydryl groups in relation to the metabolism and motility of human spermatozoa

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

The spermostatic and microbicidal actions of quinones and maleimides: toward a dual-purpose contraceptive agent.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Multiple forms of redox activity in populations of human spermatozoa.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Optimization of parameters for semiempirical methods V: Modification of NDDO approximations and application to 70 elements

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Cis-unsaturated fatty acids stimulate reactive oxygen species generation and lipid peroxidation in human spermatozoa.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Stimulation of mitochondrial reactive oxygen species production by unesterified, unsaturated fatty acids in defective human spermatozoa.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Prolactin exerts a prosurvival effect on human spermatozoa via mechanisms that involve the stimulation of Akt phosphorylation and suppression of caspase activation and capacitation.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Male genital tract antioxidant enzymes--their ability to preserve sperm DNA integrity

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

NOX5 in human spermatozoa: expression, function, and regulation

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Mammalian sperm metabolism: oxygen and sugar, friend and foe.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Reactive oxygen species and human spermatozoa: physiology and pathology

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Chelators as antidotes of metal toxicity: therapeutic and experimental aspects

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Biochemistry of the induction and prevention of lipoperoxidative damage in human spermatozoa

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Cytoprotective mechanisms of carbonyl scavenging drugs in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

DNA damage induced by peroxynitrite: subsequent biological effects

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Redox regulation of human OGG1 activity in response to cellular oxidative stress

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Modulation of Chlamydomonas reinhardtii flagellar motility by redox poise.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

D-penicillamine and granulosa cells can effectively extend the fertile life span of bovine frozen-thawed spermatozoa in vitro: effect on fertilization and polyspermy

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.112.102020

21 January 2018

Identifiers

10.1095/BIOLREPROD.112.102020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22933515%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22933515%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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