(Q58414922)

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Copper-mediated formation of hydrogen peroxide from the amylin peptide: A novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

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1 January 2020

Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus? (English)

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17617411%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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molecular biology

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structural biology

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Nigel J Fullwood

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1 January 2020

Matthew J German

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1 January 2020

Fuyuki Kametani

8

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1 January 2020

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Atef Masad

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1 January 2020

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Lee Hayes

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1 January 2020

Stuart Turnbull

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1 January 2020

Brian J Tabner

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1 January 2020

Leanne J Cooper

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1 January 2020

Omar M A El-Agnaf

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2 July 2007

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1 January 2020

1 reference

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1 January 2020

581

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1 January 2020

18

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1 January 2020

3489-3493

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1 January 2020

Role of islet amyloid in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Diabetes mellitus in Macaca mulatta monkeys is characterised by islet amyloidosis and reduction in beta-cell population.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Amyloid peptides are toxic via a common oxidative mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Thiol reducing compounds prevent human amylin-evoked cytotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Intracellular amyloidogenesis by human islet amyloid polypeptide induces apoptosis in COS-1 cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.061

21 January 2018

Identifiers

10.1016/J.FEBSLET.2007.06.061

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17617411%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17617411%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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