(Q58485351)

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Microtubule-Affinity Regulating Kinase (MARK) Is Tightly Associated with Neurofibrillary Tangles in Alzheimer Brain: A Fluorescence Resonance Energy Transfer Study

scientific article published on 01 November 2000

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scholarly article

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Europe PubMed Central

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2 November 2019

Microtubule-affinity regulating kinase (MARK) is tightly associated with neurofibrillary tangles in Alzheimer brain: a fluorescence resonance energy transfer study (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11089574%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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2 November 2019

Eva-Maria Mandelkow

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E M Mandelkow

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2 November 2019

author name string

J Y Chin

1

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2 November 2019

R B Knowles

2

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2 November 2019

A Schneider

3

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2 November 2019

B T Hyman

6

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2 November 2019

publication date

1 November 2000

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2 November 2019

Journal of Neuropathology & Experimental Neurology

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2 November 2019

59

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2 November 2019

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2 November 2019

966-971

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2 November 2019

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Structural stability of paired helical filaments requires microtubule-binding domains of Tau: A model for self-association

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Levels of tau phosphorylation at different sites in Alzheimer disease brain.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Hyperphosphorylation of tau in PHF

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Demonstration by fluorescence resonance energy transfer of a close association between activated MAP kinase and neurofibrillary tangles: implications for MAP kinase activation in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Resonance energy transfer: methods and applications

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Glycogen synthase kinase 3 phosphorylation of different residues in the presence of different factors: analysis on tau protein.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Possible role of tau protein kinases in pathogenesis of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.11.966

21 January 2018

Identifiers

10.1093/JNEN/59.11.966

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11089574%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11089574%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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