(Q58571804)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240430%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Control of the stereo-selectivity of styrene epoxidation by cytochrome P450 BM3 using structure-based mutagenesis (English)

1 reference

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20 January 2020

1 reference

1

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20 January 2020

Paul Cullis

2

1 reference

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20 January 2020

Emma L. Raven

3

1 reference

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20 January 2020

Gordon Roberts

4

1 reference

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20 January 2020

3

Emma Lloyd Raven

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author name string

Wei-Cheng Huang

1

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Paul M. Cullis

2

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Gordon C. K. Roberts

4

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publication date

17 January 2011

1 reference

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20 January 2020

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20 January 2020

volume

3

1 reference

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20 January 2020

issue

4

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20 January 2020

page(s)

410-416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240430%20AND%20SRC:MED&resulttype=core&format=json

Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency

20 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Cyclopropyl containing fatty acids as mechanistic probes for cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

P450 BM3: the very model of a modern flavocytochrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Intermediates in P450 catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Structural aspects of ligand binding to and electron transfer in bacterial and fungal P450s

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

P450BM-3 and other inducible bacterial P450 cytochromes: biochemistry and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Cytochromes P450 as versatile biocatalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450BM3 demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

A panel of cytochrome P450 BM3 variants to produce drug metabolites and diversify lead compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Desaturation of alkylbenzenes by cytochrome P450(BM3) (CYP102A1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

A highly active single-mutation variant of P450BM3 (CYP102A1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Rational design of a minimal and highly enriched CYP102A1 mutant library with improved regio-, stereo- and chemoselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Pivotal role of water in the mechanism of P450BM-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Residue size at position 87 of cytochrome P450 BM-3 determines its stereoselectivity in propylbenzene and 3-chlorostyrene oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent beta-adrenergic agonist virtually specific for beta 3 receptors. A promising antidiabetic and antiobesity agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Development and validation of a genetic algorithm for flexible docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Prediction of binding modes for ligands in the cytochromes P450 and other heme-containing proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

Preparative use of isolated CYP102 monooxygenases -- a critical appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

A screening system for the directed evolution of epoxygenases: importance of position 184 in P450 BM3 for stereoselective styrene epoxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MT00082E

21 January 2018

Identifiers

DOI

10.1039/C0MT00082E

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240430%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference