(Q58617552)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

John M Krill-Burger

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Francisca Vazquez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Jesse S Boehm

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Todd Golub

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

William C Hahn

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Aviad Tsherniak

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

13

David E Root

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

author name string

James M McFarland

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Guillaume Kugener

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Joshua M Dempster

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Phillip G Montgomery

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Jordan G Bryan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Thomas M Green

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

language of work or name

English

0 references

publication date

2 November 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

page(s)

4610

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

1 May 2020

copyright license

start time

2 November 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/s41467-018-06916-5

0 references

cites work

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Defining a Cancer Dependency Map.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

A scored human protein-protein interaction network to catalyze genomic interpretation.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

ScreenBEAM: a novel meta-analysis algorithm for functional genomics screens via Bayesian hierarchical modeling

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Simultaneous analysis of large-scale RNAi screens for pathogen entry

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Cancer vulnerabilities unveiled by genomic loss

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

siRNA off-target effects in genome-wide screens identify signaling pathway members

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

CORUM: the comprehensive resource of mammalian protein complexes--2009

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Highly parallel identification of essential genes in cancer cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

A probability-based approach for the analysis of large-scale RNAi screens.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

pcaMethods--a bioconductor package providing PCA methods for incomplete data

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6214982

PPI4DOCK: large scale assessment of the use of homology models in free docking over more than 1000 realistic targets.

30 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-06916-5

inferred from DOI database lookup

7 January 2021

based on heuristic

A Limited Memory Algorithm for Bound Constrained Optimization

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-06916-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41467-018-06916-5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389920%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference