(Q58681411)

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Characterization of drug metabolizing activities in pig hepatocytes for use in bioartificial liver devices: comparison with other hepatic cellular models

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31 October 2019

Characterization of drug metabolizing activities in pig hepatocytes for use in bioartificial liver devices: comparison with other hepatic cellular models (English)

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31 October 2019

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31 October 2019

José V Castell

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31 October 2019

Luis Gómez-Lechón Quirós

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M J Gómez-Lechón

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31 October 2019

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1 September 1999

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31 October 2019

Journal of Hepatology

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31 October 2019

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31 October 2019

542-549

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31 October 2019

3

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31 October 2019

Use of bioartificial and artificial liver support devices

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7 January 2021

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In vitro evaluation of a novel bioreactor based on an integral oxygenator and a spirally wound nonwoven polyester matrix for hepatocyte culture as small aggregates.

1 reference

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7 January 2021

based on heuristic

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Use of human hepatocyte cultures for drug metabolism studies

1 reference

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7 January 2021

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Evaluation of the xenobiotic biotransformation capability of six rodent hepatoma cell lines in comparison with rat hepatocytes

1 reference

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7 January 2021

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Primary culture of rat hepatocytes entrapped in cylindrical collagen gels: an in vitro system with application to the bioartificial liver. Rat hepatocytes cultured in cylindrical collagen gels

1 reference

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7 January 2021

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Extended liver-specific functions of porcine hepatocyte spheroids entrapped in collagen gel.

1 reference

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7 January 2021

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Functional activity of isolated pig hepatocytes attached to different extracellular matrix substrates. Implication for application of pig hepatocytes in a bioartificial liver

1 reference

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7 January 2021

based on heuristic

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Isolation and culture of porcine hepatocytes for artificial liver support.

1 reference

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7 January 2021

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Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

1 reference

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7 January 2021

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Expression of modified human cytochrome P450 1A2 in Escherichia coli: stabilization, purification, spectral characterization, and catalytic activities of the enzyme.

1 reference

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7 January 2021

based on heuristic

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Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse.

1 reference

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7 January 2021

based on heuristic

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Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

1 reference

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7 January 2021

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Purification and characterization of cytochrome P450 2E2 from hepatic microsomes of neonatal rabbits

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

1 reference

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7 January 2021

based on heuristic

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Isolation and characterization of four cytochrome P450 isozymes from untreated and phenobarbital-treated beagle dogs

1 reference

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7 January 2021

based on heuristic

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7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980049-X

7 January 2021

based on heuristic

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Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450.

1 reference

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7 January 2021

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Cytochrome P-450 in human liver microsomes: high-performance liquid chromatographic isolation of three forms and their characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980049-X

7 January 2021

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Biochemical functionality and recovery of hepatocytes after deep freezing storage

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980049-X

7 January 2021

based on heuristic

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A Microassay for Measuring Cytochrome P450IA1 and Cytochrome P450IIB1 Activities in Intact Human and Rat Hepatocytes Cultured on 96-Well Plates

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980049-X

7 January 2021

based on heuristic

inferred from DOI database lookup

7-ethoxycoumarin deethylase activity as a convenient measure of liver drug metabolizing enzymes: Regulation in cultured rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980049-X

7 January 2021

based on heuristic

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Use of in vitro human metabolism studies in drug development. An industrial perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980049-X

7 January 2021

based on heuristic

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P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980049-X

7 January 2021

based on heuristic

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Quantitation of cytochrome P450 enzymes (CYP1A1/2, 2B11, 2C21 and 3A12) in dog liver microsomes by enzyme-linked immunosorbent assay.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980049-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0168-8278(99)80049-X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10488716%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10488716%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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