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Structure of a volume-regulated anion channel of the LRRC8 family
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Europe PubMed Central
PubMed publication ID
29769723
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29769723%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
title
Structure of a volume-regulated anion channel of the LRRC8 family
(English)
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Europe PubMed Central
PubMed publication ID
29769723
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29769723%20AND%20SRC:MED&resulttype=core&format=json
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26 March 2020
main subject
Leucine rich repeat containing 8 VRAC subunit A
1 reference
stated in
GOA release 2020-03-11
anion transmembrane transport
1 reference
stated in
GOA release 2020-03-11
Leucine rich repeat containing 8A VRAC subunit A
1 reference
stated in
GOA release 2020-03-11
Leucine rich repeat containing 8 family, member C
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GOA release 2020-03-11
author
Marta Sawicka
series ordinal
2
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Europe PubMed Central
PubMed publication ID
29769723
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retrieved
26 March 2020
Andy K M Lam
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3
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Europe PubMed Central
PubMed publication ID
29769723
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26 March 2020
Cristina Paulino
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4
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PubMed publication ID
29769723
reference URL
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26 March 2020
Dawid Deneka
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Dawid Deneka
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1
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Raimund Dutzler
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5
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Europe PubMed Central
PubMed publication ID
29769723
reference URL
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retrieved
26 March 2020
language of work or name
English
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publication date
16 May 2018
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Europe PubMed Central
PubMed publication ID
29769723
reference URL
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retrieved
26 March 2020
published in
Nature
1 reference
stated in
Europe PubMed Central
PubMed publication ID
29769723
reference URL
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retrieved
26 March 2020
volume
558
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Europe PubMed Central
PubMed publication ID
29769723
reference URL
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retrieved
26 March 2020
issue
7709
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Europe PubMed Central
PubMed publication ID
29769723
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29769723%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
page(s)
254-259
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Europe PubMed Central
PubMed publication ID
29769723
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29769723%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
cites work
VRACs and other ion channels and transporters in the regulation of cell volume and beyond
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physiology of cell volume regulation in vertebrates.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory volume decrease in cultured astrocytes. II. Permeability pathway to amino acids and polyols
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LRRC8A protein is indispensable for swelling-activated and ATP-induced release of excitatory amino acids in rat astrocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Properties of volume-regulated anion channels in mammalian cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A congenital mutation of the novel gene LRRC8 causes agammaglobulinemia in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LRRC8 proteins share a common ancestor with pannexins, and may form hexameric channels involved in cell-cell communication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the connexin 26 gap junction channel at 3.5 A resolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The leucine-rich repeat structure.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A tissue-specific atlas of mouse protein phosphorylation and expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation and Anion Selectivity of Volume-regulated Anion Channels (VRACs) Depend on C-terminal Residues of the First Extracellular Loop.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defining the factors that affect solute permeation of gap junction channels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective permeability of gap junction channels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of a Cl- current by hypotonic volume increase in human endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual role of ATP in supporting volume-regulated chloride channels in mouse fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cisplatin activates volume sensitive LRRC8 channel mediated currents in Xenopus oocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A versatile and efficient high-throughput cloning tool for structural biology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
One-step purification of recombinant proteins using a nanomolar-affinity streptavidin-binding peptide, the SBP-Tag
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mScarlet: a bright monomeric red fluorescent protein for cellular imaging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Refractive index-based determination of detergent concentration and its application to the study of membrane proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phasercrystallographic software
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PHENIX: building new software for automated crystallographic structure determination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The I-TASSER Suite: protein structure and function prediction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coot: model-building tools for molecular graphics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Automated electron microscope tomography using robust prediction of specimen movements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTFFIND4: Fast and accurate defocus estimation from electron micrographs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RELION: implementation of a Bayesian approach to cryo-EM structure determination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sampling the conformational space of the catalytic subunit of human γ-secretase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of overfitting in cryo-EM structure determination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bsoft: image processing and molecular modeling for electron microscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
One number does not fit all: mapping local variations in resolution in cryo-EM reconstructions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
REFMAC5 for the refinement of macromolecular crystal structures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UCSF Chimera--a visualization system for exploratory research and analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recent developments in the CCP-EM software suite.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HOLE: a program for the analysis of the pore dimensions of ion channel structural models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MOLEonline 2.0: interactive web-based analysis of biomacromolecular channels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CHARMM: A program for macromolecular energy, minimization, and dynamics calculations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41586-018-0134-Y
retrieved
7 January 2021
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Identifiers
DOI
10.1038/S41586-018-0134-Y
1 reference
stated in
Europe PubMed Central
PubMed publication ID
29769723
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29769723%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
Dimensions Publication ID
1103975537
0 references
PubMed publication ID
29769723
1 reference
stated in
Europe PubMed Central
PubMed publication ID
29769723
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29769723%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
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