(Q59295353)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17185390%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

title

Age-dependent accumulation of mtDNA mutations in murine hematopoietic stem cells is modulated by the nuclear genetic background (English)

1 reference

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23 December 2019

1

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23 December 2019

author name string

Jichun Chen

4

1 reference

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23 December 2019

Felicia M Ellison

2

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23 December 2019

J Philip McCoy

3

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23 December 2019

Neal S Young

5

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23 December 2019

publication date

21 December 2006

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23 December 2019

published in

Human Molecular Genetics

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23 December 2019

volume

16

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23 December 2019

issue

3

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23 December 2019

page(s)

286-294

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A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

23 December 2019

cites work

1 reference

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Mitochondrial DNA and ageing

21 January 2018

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The biologic clock: the mitochondria?

21 January 2018

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Free radical theory of aging: an update: increasing the functional life span

21 January 2018

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The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations

21 January 2018

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Oxidative damage to mitochondrial DNA in atrial muscle of patients with atrial fibrillation.

21 January 2018

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Mitochondrial DNA mutations as a fundamental mechanism in physiological declines associated with aging

21 January 2018

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The mitochondrial theory of aging: dead or alive?

21 January 2018

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The free radical fantasy: a panoply of paradoxes.

21 January 2018

1 reference

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Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

21 January 2018

1 reference

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Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

21 January 2018

1 reference

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Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy.

21 January 2018

1 reference

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Deletion of Ku86 causes early onset of senescence in mice

21 January 2018

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

21 January 2018

1 reference

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Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging?

21 January 2018

1 reference

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Mitochondrial mutations in mammalian aging: an over-hasty about-turn?

21 January 2018

1 reference

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Biology of normal and acute myeloid leukemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Genetic control of stem cells: implications for aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Hematopoiesis in the elderly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

The aging of hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Hematopoietic stem cells do not engraft with absolute efficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Development and aging of primitive hematopoietic stem cells in BALB/cBy mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Genetic regulation of primitive hematopoietic stem cell senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Age-associated characteristics of murine hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Mitochondrial DNA sequence variation in single cells from leukemia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Mitochondrial DNA spectra of single human CD34+ cells, T cells, B cells, and granulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Marked mitochondrial DNA sequence heterogeneity in single CD34+ cell clones from normal adult bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Revisiting the mouse mitochondrial DNA sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Free radicals in the physiological control of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Radical medicine: treating ageing to cure disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

Accumulation of point mutations in mitochondrial DNA of aging mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL457

21 January 2018

Identifiers

DOI

10.1093/HMG/DDL457

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17185390%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

1 reference