(Q59339672)

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5 May 2020

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1

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5 May 2020

Sonu Kumar

2

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5 May 2020

Joel Allen

3

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5 May 2020

Colin J Mann

6

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Jeffrey Copps

8

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Anita Sarkar

9

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Devin Sok

12

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Max Crispin

13

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5 May 2020

Andrew B Ward

14

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5 May 2020

David Nemazee

15

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5 May 2020

Dennis R. Burton

16

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Ian A Wilson

17

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Jiang Zhu

18

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5 May 2020

11

Gabriel Ozorowski

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5 May 2020

author name string

Deli Huang

4

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5 May 2020

Xiaohe Lin

5

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5 May 2020

Karen L Saye-Francisco

7

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5 May 2020

Gabrielle S Blizard

10

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5 May 2020

language of work or name

English

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publication date

November 2018

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published in

Science Advances

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5 May 2020

volume

4

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5 May 2020

issue

11

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5 May 2020

page(s)

eaau6769

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30474059%20AND%20SRC:MED&resulttype=core&format=json

Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG.

5 May 2020

cites work

1 reference

12 December 2020

Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides.

1 reference

12 December 2020

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

1 reference

12 December 2020

Accessing the Kabat antibody sequence database by computer

1 reference

12 December 2020

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

1 reference

12 December 2020

Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution

1 reference

12 December 2020

Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins

1 reference

12 December 2020

Timing the ancestor of the HIV-1 pandemic strains

1 reference

12 December 2020

Industrial choices for protein production by large-scale cell culture

1 reference

12 December 2020

Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin

1 reference

12 December 2020

Diversity considerations in HIV-1 vaccine selection

1 reference

12 December 2020

Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

1 reference

12 December 2020

Consensus and Ancestral State HIV Vaccines

1 reference

12 December 2020

Topology representing network enables highly accurate classification of protein images taken by cryo electron-microscope without masking.

1 reference

12 December 2020

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

12 December 2020

Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein

1 reference

12 December 2020

Molecular crowding enhances native state stability and refolding rates of globular proteins

1 reference

12 December 2020

Fragmentation of negative ions from carbohydrates: part 1. Use of nitrate and other anionic adducts for the production of negative ion electrospray spectra from N-linked carbohydrates

1 reference

12 December 2020

Fragmentation of negative ions from carbohydrates: part 2. Fragmentation of high-mannose N-linked glycans

1 reference

12 December 2020

Fragmentation of negative ions from carbohydrates: part 3. Fragmentation of hybrid and complex N-linked glycans

1 reference

12 December 2020

Automated molecular microscopy: the new Leginon system

1 reference

12 December 2020

Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant

1 reference

12 December 2020

Ancestral and consensus envelope immunogens for HIV-1 subtype C.

1 reference

12 December 2020

A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses

1 reference

12 December 2020

Exploiting the defensive sugars of HIV-1 for drug and vaccine design

1 reference

12 December 2020

Replicating and non-replicating viral vectors for vaccine development

1 reference

12 December 2020

Virus-like particles-universal molecular toolboxes

1 reference

12 December 2020

Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry

1 reference

12 December 2020

A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys

1 reference

12 December 2020

The coming of age of virus-like particle vaccines

1 reference

12 December 2020

Development of a single column method for the separation of lipid- and protein-derived oligosaccharides

1 reference

12 December 2020

Appion: an integrated, database-driven pipeline to facilitate EM image processing

1 reference

12 December 2020

DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

1 reference

12 December 2020

Phasercrystallographic software

1 reference

12 December 2020

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

1 reference

12 December 2020

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

1 reference

12 December 2020

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

12 December 2020

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

12 December 2020

Features and development of Coot

1 reference

12 December 2020

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

1 reference

12 December 2020

The JCSG high-throughput structural biology pipeline

1 reference

12 December 2020

DNA vaccines: an historical perspective and view to the future

1 reference

12 December 2020

Broad neutralization coverage of HIV by multiple highly potent antibodies

1 reference

12 December 2020

1 reference

12 December 2020

Anti-HIV B Cell lines as candidate vaccine biosensors

1 reference

12 December 2020

Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development

1 reference

12 December 2020

Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1

1 reference

12 December 2020

Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development

1 reference

12 December 2020

Phenotypic properties of transmitted founder HIV-1

1 reference

12 December 2020

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

1 reference

12 December 2020

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

1 reference

12 December 2020

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

1 reference

12 December 2020

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

1 reference

12 December 2020

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

1 reference

12 December 2020

Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1.

1 reference

12 December 2020

Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies

1 reference

12 December 2020

Generation of a universal CD4 memory T cell recall peptide effective in humans, mice and non-human primates

1 reference

12 December 2020

Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

1 reference

12 December 2020

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

1 reference

12 December 2020

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

1 reference

12 December 2020

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

1 reference

12 December 2020

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

1 reference

12 December 2020

Why HIV virions have low numbers of envelope spikes: implications for vaccine development

1 reference

12 December 2020

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

1 reference

12 December 2020

Structural evolution of glycan recognition by a family of potent HIV antibodies

1 reference

12 December 2020

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

1 reference

12 December 2020

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene

1 reference

12 December 2020

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

1 reference

12 December 2020

Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design

1 reference

12 December 2020

Antibody responses to envelope glycoproteins in HIV-1 infection

1 reference

12 December 2020

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers

1 reference

12 December 2020

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

1 reference

12 December 2020

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

1 reference

12 December 2020

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

1 reference

12 December 2020

Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens

1 reference

12 December 2020

Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity

1 reference

12 December 2020

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

1 reference

12 December 2020

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.

1 reference

12 December 2020

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

1 reference

12 December 2020

Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers

1 reference

12 December 2020

Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

1 reference

12 December 2020

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

1 reference

12 December 2020

Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein

1 reference

12 December 2020

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

1 reference

12 December 2020

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

1 reference

12 December 2020

Design of a hyperstable 60-subunit protein dodecahedron. [corrected]

1 reference

12 December 2020

Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.

1 reference

12 December 2020

Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

1 reference

12 December 2020

Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates

1 reference

12 December 2020

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

1 reference

12 December 2020

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

1 reference

12 December 2020

Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Molecular Architecture of the Cleavage-Dependent Mannose Patch on a Soluble HIV-1 Envelope Glycoprotein Trimer

1 reference

12 December 2020

An accelerated rabies vaccine schedule based on toll-like receptor 3 (TLR3) agonist PIKA adjuvant augments rabies virus specific antibody and T cell response in healthy adult volunteers

1 reference

12 December 2020

The quest for an antibody-based HIV vaccine

1 reference

12 December 2020

Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem

1 reference

12 December 2020

Native-like Env trimers as a platform for HIV-1 vaccine design

1 reference

12 December 2020

The HIV-1 envelope glycoprotein structure: nailing down a moving target

1 reference

12 December 2020

Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers

1 reference

12 December 2020

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

1 reference

12 December 2020

Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein

1 reference

12 December 2020

Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes.

1 reference

12 December 2020

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

1 reference

12 December 2020

Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein

1 reference

12 December 2020

Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach

1 reference

12 December 2020

Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers

1 reference

12 December 2020

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

1 reference

12 December 2020

Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike

1 reference

12 December 2020

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

1 reference

12 December 2020

High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers

1 reference

12 December 2020

cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate

1 reference

12 December 2020

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIADV.AAU6769

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30474059%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30474059%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

PubMed publication ID

30474059

1 reference