(Q39108730)

9 September 2017

Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem (English)

1 reference

9 September 2017

1 reference

T follicular helper cell

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28133798%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Shane Crotty

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28133798%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Colin Havenar-Daughton

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28133798%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

1 reference

1 January 2017

1 reference

9 September 2017

Immunological Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28133798%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28133798%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28133798%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

49-61

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28133798%20AND%20SRC:MED&resulttype=core&format=json

Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

10 June 2020

cites work

1 reference

Antibodies in HIV-1 vaccine development and therapy

21 January 2018

1 reference

Broad neutralization coverage of HIV by multiple highly potent antibodies

21 January 2018

1 reference

Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design

21 January 2018

1 reference

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

21 January 2018

1 reference

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

21 January 2018

1 reference

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

21 January 2018

1 reference

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.

21 January 2018

1 reference

Progress in HIV-1 vaccine development.

21 January 2018

1 reference

Harnessing CD4⁺ T cell responses in HIV vaccine development

21 January 2018

1 reference

Immune history profoundly affects broadly protective B cell responses to influenza.

21 January 2018

1 reference

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

21 January 2018

1 reference

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

21 January 2018

1 reference

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

21 January 2018

1 reference

New approaches to HIV vaccine development

21 January 2018

1 reference

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

21 January 2018

1 reference

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

21 January 2018

1 reference

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

21 January 2018

1 reference

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

21 January 2018

1 reference

21 January 2018

1 reference

T follicular helper cell differentiation, function, and roles in disease

21 January 2018

1 reference

Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

21 January 2018

1 reference

Clonal selection in the germinal centre by regulated proliferation and hypermutation

21 January 2018

1 reference

B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity

21 January 2018

1 reference

HUMORAL IMMUNITY. T cell help controls the speed of the cell cycle in germinal center B cells.

21 January 2018

1 reference

A brief history of T cell help to B cells

21 January 2018

1 reference

A Blueprint for HIV Vaccine Discovery

21 January 2018

1 reference

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

21 January 2018

1 reference

Inadequate T follicular cell help impairs B cell immunity during HIV infection.

21 January 2018

1 reference

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

21 January 2018

1 reference

CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses.

21 January 2018

1 reference

Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion

21 January 2018

1 reference

Early preservation of CXCR5+ PD-1+ helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection

21 January 2018

1 reference

Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies

21 January 2018

1 reference

How T cells earn the follicular rite of passage

21 January 2018

1 reference

Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation

21 January 2018

1 reference

CXCL13 is a plasma biomarker of germinal center activity

21 January 2018

1 reference

Unique gene expression program of human germinal center T helper cells

21 January 2018

1 reference

Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease

21 January 2018

1 reference

CXCL13 antibody for the treatment of autoimmune disorders

21 January 2018

1 reference

Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection

21 January 2018

1 reference

CD4 T follicular helper cell dynamics during SIV infection

21 January 2018

1 reference

Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection

21 January 2018

1 reference

Regulatory and Helper Follicular T Cells and Antibody Avidity to Simian Immunodeficiency Virus Glycoprotein 120.

21 January 2018

1 reference

Early lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection

21 January 2018

1 reference

Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection

21 January 2018

1 reference

Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

21 January 2018

1 reference

Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

21 January 2018

1 reference

COMPASS identifies T-cell subsets correlated with clinical outcomes

21 January 2018

1 reference

HIV-1 Antibody Neutralization Breadth Is Associated with Enhanced HIV-Specific CD4+ T Cell Responses

21 January 2018

1 reference

Circulating HIV-Specific Interleukin-21(+)CD4(+) T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions

21 January 2018

1 reference

Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques

21 January 2018

1 reference

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

21 January 2018

1 reference

Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.

21 January 2018

1 reference

Diminished viral control during simian immunodeficiency virus infection is associated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa.

21 January 2018

1 reference

Multiple Origins of Virus Persistence during Natural Control of HIV Infection

21 January 2018

1 reference

Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

21 January 2018

1 reference

A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.

21 January 2018

1 reference

High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40).

21 January 2018

1 reference

Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions

21 January 2018

1 reference

Fine-needle aspiration (FNA) biopsy: historical aspects.

21 January 2018

1 reference

Sampling lymphoid tissue cells by ultrasound-guided fine needle aspiration of lymph nodes in HIV-infected patients

21 January 2018

1 reference

Long-term kinetics of T cell production in HIV-infected subjects treated with highly active antiretroviral therapy

21 January 2018

1 reference

Serial study of lymph node cell subsets using fine needle aspiration in pigtail macaques.

21 January 2018

1 reference

Antibody responses to envelope glycoproteins in HIV-1 infection

21 January 2018

1 reference

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

21 January 2018

1 reference

Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies

21 January 2018

1 reference

Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

21 January 2018

1 reference

Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies

21 January 2018

1 reference

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

21 January 2018

1 reference

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

21 January 2018

1 reference

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

21 January 2018

1 reference

Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

21 January 2018

1 reference

Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

21 January 2018

1 reference

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

21 January 2018

1 reference

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

21 January 2018

1 reference

Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers

21 January 2018

1 reference

Prevalence of cross-reactive HIV-1-neutralizing activity in HIV-1-infected patients with rapid or slow disease progression.

21 January 2018

1 reference

Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection

21 January 2018

1 reference

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

21 January 2018

1 reference

Specificity of the autologous neutralizing antibody response

21 January 2018

1 reference

Antibody neutralization and escape by HIV-1

21 January 2018

1 reference

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

21 January 2018

1 reference

The role of antibodies in HIV vaccines

21 January 2018

1 reference

Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Ev

21 January 2018

1 reference

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

21 January 2018

1 reference

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

21 January 2018

1 reference

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

21 January 2018

1 reference

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

21 January 2018

1 reference

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

21 January 2018

1 reference

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

21 January 2018

1 reference

The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response

21 January 2018

1 reference

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

21 January 2018

1 reference

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

21 January 2018

1 reference

Clonal and cellular dynamics in germinal centers

21 January 2018

1 reference

Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced

21 January 2018

1 reference

A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center

21 January 2018

1 reference

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

21 January 2018

1 reference

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

21 January 2018

1 reference

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

21 January 2018

1 reference

Humoral immunity. Apoptosis and antigen affinity limit effector cell differentiation of a single naïve B cell

21 January 2018

1 reference

Visualizing antibody affinity maturation in germinal centers

21 January 2018

1 reference

Complex Antigens Drive Permissive Clonal Selection in Germinal Centers

21 January 2018

1 reference

Broadly neutralizing antiviral antibodies

21 January 2018

1 reference

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants

21 January 2018

1 reference

Germinal center selection and the antibody response to influenza

21 January 2018

1 reference

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

21 January 2018

1 reference

Programming the magnitude and persistence of antibody responses with innate immunity

21 January 2018

1 reference

Follicular Helper T Cells

21 January 2018

1 reference

Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination

21 January 2018

1 reference

Activin A programs the differentiation of human TFH cells

21 January 2018

1 reference

A High-Dimensional Atlas of Human T Cell Diversity Reveals Tissue-Specific Trafficking and Cytokine Signatures.

21 January 2018

1 reference

Human Circulating T Follicular Helper Cell Subsets in Health and Disease

21 January 2018

1 reference

Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

21 January 2018

1 reference

Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12.

21 January 2018

1 reference

Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.

21 January 2018

1 reference

Molecular Mechanisms Regulating T Helper 1 versus T Follicular Helper Cell Differentiation in Humans.

21 January 2018

1 reference

The cytokine TGF-β co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells

21 January 2018

1 reference

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/IMR.12512

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28133798%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference