(Q36112751)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27560183%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design (English)

1 reference

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21 March 2020

1 reference

1 reference

3

1 reference

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21 March 2020

Anita Sarkar

5

1 reference

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21 March 2020

Jessica Hsueh

11

1 reference

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21 March 2020

Skye Macpherson

15

1 reference

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21 March 2020

Fabian Sesterhenn

18

1 reference

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21 March 2020

24

William R Schief

1 reference

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21 March 2020

23

Dennis R Burton

1 reference

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21 March 2020

author name string

Joseph G Jardine

1

1 reference

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21 March 2020

Devin Sok

2

1 reference

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21 March 2020

Bryan Briney

4

1 reference

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21 March 2020

Chi-Hui Liang

6

1 reference

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21 March 2020

Erin A Scherer

7

1 reference

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21 March 2020

Carole J Henry Dunand

8

1 reference

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21 March 2020

Yumiko Adachi

9

1 reference

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21 March 2020

Devan Diwanji

10

1 reference

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21 March 2020

Meaghan Jones

12

1 reference

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21 March 2020

Oleksandr Kalyuzhniy

13

1 reference

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21 March 2020

Michael Kubitz

14

1 reference

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21 March 2020

Matthias Pauthner

16

1 reference

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21 March 2020

Karen L Saye-Francisco

17

1 reference

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21 March 2020

Patrick C Wilson

19

1 reference

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21 March 2020

Denise M Galloway

20

1 reference

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21 March 2020

Robyn L Stanfield

21

1 reference

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21 March 2020

Ian A Wilson

22

1 reference

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21 March 2020

publication date

25 August 2016

1 reference

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21 March 2020

1 reference

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21 March 2020

volume

12

1 reference

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21 March 2020

issue

8

1 reference

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21 March 2020

page(s)

e1005815

1 reference

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Creative Commons Attribution 4.0 International

21 March 2020

copyright license

start time

25 August 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

2 October 2017

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Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

2 October 2017

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Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

2 October 2017

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HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies

2 October 2017

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2 October 2017

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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

2 October 2017

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Characteristics of memory B cells elicited by a highly efficacious HPV vaccine in subjects with no pre-existing immunity

2 October 2017

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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

2 October 2017

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Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

2 October 2017

1 reference

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Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

2 October 2017

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Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

2 October 2017

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Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

2 October 2017

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Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

2 October 2017

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Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization

2 October 2017

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Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

2 October 2017

1 reference

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Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

2 October 2017

1 reference

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Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

2 October 2017

1 reference

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2 October 2017

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Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline

2 October 2017

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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

2 October 2017

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

2 October 2017

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2 October 2017

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2 October 2017

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Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool

2 October 2017

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Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

2 October 2017

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HIV-1 neutralizing antibodies: understanding nature's pathways

2 October 2017

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Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

2 October 2017

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Immunogenicity of 2 doses of HPV vaccine in younger adolescents vs 3 doses in young women: a randomized clinical trial

2 October 2017

1 reference

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Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

2 October 2017

1 reference

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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

2 October 2017

1 reference

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Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

2 October 2017

1 reference

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Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

2 October 2017

1 reference

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Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

2 October 2017

1 reference

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Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

2 October 2017

1 reference

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Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.

2 October 2017

1 reference

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Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study

2 October 2017

1 reference

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PANDAseq: paired-end assembler for illumina sequences

2 October 2017

1 reference

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HIV-1 neutralization coverage is improved by combining monoclonal antibodies that target independent epitopes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Broad neutralization coverage of HIV by multiple highly potent antibodies

2 October 2017

1 reference

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

PHENIX: a comprehensive Python-based system for macromolecular structure solution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Challenges for structure-based HIV vaccine design

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Phasercrystallographic software

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

IMGT, the international ImMunoGeneTics information system.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

GLYCAM06: a generalizable biomolecular force field. Carbohydrates

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Inference of macromolecular assemblies from crystalline state

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Autoreactivity in human IgG+ memory B cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Comparison of multiple Amber force fields and development of improved protein backbone parameters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Antibody vs. HIV in a clash of evolutionary titans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

The Amber biomolecular simulation programs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Coot: model-building tools for molecular graphics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999182

Comparison of simple potential functions for simulating liquid water

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005815

10.1371/JOURNAL.PPAT.1005815

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27560183%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27560183%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference