(Q37213491)

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Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

scientific article published on May 2016

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scholarly article

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Europe PubMed Central

PMC publication ID

19 August 2017

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch (English)

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Europe PubMed Central

PMC publication ID

19 August 2017

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Elise Landais

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19 August 2017

Pascal Poignard

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Pascal Poignard

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19 August 2017

Sergei L. Kosakovsky Pond

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Sergei L Kosakovsky Pond

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Chi-Huey Wong

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Dennis R. Burton

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Dennis R Burton

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19 August 2017

author name string

Daniel T MacLeod

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Nancy M Choi

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Bryan Briney

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Fernando Garces

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Lorena S Ver

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Ben Murrell

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Terri Wrin

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William Kilembe

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Chi-Hui Liang

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Alejandra Ramos

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Chaoran B Bian

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Lalinda Wickramasinghe

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Leopold Kong

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Kemal Eren

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Chung-Yi Wu

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IAVI Protocol C Investigators & The IAVI African HIV Research Network

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Ian A Wilson

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19 August 2017

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publication date

1 May 2016

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19 August 2017

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19 August 2017

44

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5

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19 August 2017

1215-1226

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Europe PubMed Central

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19 August 2017

Clonify: unseeded antibody lineage assignment from next-generation sequencing data

1 reference

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Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

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Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

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Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies

1 reference

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Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

1 reference

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Polyreactivity and autoreactivity among HIV-1 antibodies

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Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

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9 September 2017

Structural evolution of glycan recognition by a family of potent HIV antibodies

1 reference

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Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

1 reference

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9 September 2017

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

1 reference

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Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

1 reference

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9 September 2017

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003182

9 September 2017

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

1 reference

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9 September 2017

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

1 reference

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9 September 2017

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

1 reference

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9 September 2017

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

1 reference

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9 September 2017

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

1 reference

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9 September 2017

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

1 reference

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9 September 2017

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

1 reference

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9 September 2017

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

1 reference

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9 September 2017

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

1 reference

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9 September 2017

Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

1 reference

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9 September 2017

Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

1 reference

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A Blueprint for HIV Vaccine Discovery

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Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

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Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes

1 reference

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B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study

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9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity

1 reference

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PANDAseq: paired-end assembler for illumina sequences

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

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Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16.

1 reference

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12 December 2020

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10.1016/J.IMMUNI.2016.04.016

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Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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