(Q59813037)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30524966%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

title

A Unique Human Immunoglobulin Heavy Chain Variable Domain-Only CD33 CAR for the Treatment of Acute Myeloid Leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30524966%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

acute myeloid leukemia

1 reference

6

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12 April 2020

author name string

Dina Schneider

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30524966%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Ying Xiong

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30524966%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Peirong Hu

3

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12 April 2020

Darong Wu

4

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12 April 2020

Weizao Chen

5

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12 April 2020

Zhongyu Zhu

7

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12 April 2020

Dimiter S Dimitrov

8

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12 April 2020

Boro Dropulic

9

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12 April 2020

Rimas J Orentas

10

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12 April 2020

language of work or name

English

0 references

publication date

22 November 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30524966%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

published in

Frontiers in Oncology

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12 April 2020

volume

8

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12 April 2020

page(s)

539

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Creative Commons Attribution 4.0 International

12 April 2020

copyright license

start time

22 November 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells

1 reference

12 December 2020

Molecular cloning, expression, and chromosomal localization of a human gene encoding the CD33 myeloid differentiation antigen

1 reference

12 December 2020

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1 reference

12 December 2020

Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.

1 reference

12 December 2020

The inhibitory effect of anti-CD33 monoclonal antibodies on AML cell growth correlates with Syk and/or ZAP-70 expression

1 reference

12 December 2020

An inducible caspase 9 safety switch for T-cell therapy

1 reference

12 December 2020

Phase III randomized multicenter study of a humanized anti-CD33 monoclonal antibody, lintuzumab, in combination with chemotherapy, versus chemotherapy alone in patients with refractory or first-relapsed acute myeloid leukemia

1 reference

12 December 2020

Primitive AML progenitors from most CD34(+) patients lack CD33 expression but progenitors from many CD34(-) AML patients express CD33.

1 reference

12 December 2020

Construction of a large phage-displayed human antibody domain library with a scaffold based on a newly identified highly soluble, stable heavy chain variable domain

1 reference

12 December 2020

Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers

1 reference

12 December 2020

Construction of a human antibody domain (VH) library

1 reference

12 December 2020

A large human domain antibody library combining heavy and light chain CDR3 diversity

1 reference

12 December 2020

Gemtuzumab ozogamicin: is there room for salvage?

1 reference

12 December 2020

Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells

1 reference

12 December 2020

Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia

1 reference

12 December 2020

A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells

1 reference

12 December 2020

In Vitro and In Vivo Antitumor Effect of Anti-CD33 Chimeric Receptor-Expressing EBV-CTL against CD33 Acute Myeloid Leukemia

1 reference

12 December 2020

Acute myeloid leukemia stem cells and CD33-targeted immunotherapy

1 reference

12 December 2020

Redirecting gene-modified T cells toward various cancer types using tagged antibodies

1 reference

12 December 2020

Clinical significance of CD33 nonsynonymous single-nucleotide polymorphisms in pediatric patients with acute myeloid leukemia treated with gemtuzumab-ozogamicin-containing chemotherapy

1 reference

12 December 2020

Gemtuzumab ozogamicin in acute myeloid leukemia: a remarkable saga about an active drug

1 reference

12 December 2020

A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia

1 reference

12 December 2020

Outcome of older patients with acute myeloid leukemia: an analysis of SEER data over 3 decades

1 reference

12 December 2020

Significance of minimal residual disease before myeloablative allogeneic hematopoietic cell transplantation for AML in first and second complete remission

1 reference

12 December 2020

T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia.

1 reference

12 December 2020

Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo.

1 reference

12 December 2020

A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy

1 reference

12 December 2020

CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia

1 reference

12 December 2020

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

1 reference

12 December 2020

Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies

1 reference

12 December 2020

A Phase I Study of Reduced-Intensity Conditioning and Allogeneic Stem Cell Transplantation Followed by Dose Escalation of Targeted Consolidation Immunotherapy with Gemtuzumab Ozogamicin in Children and Adolescents with CD33+ Acute Myeloid Leukemia

1 reference

12 December 2020

CD33 Expression and Its Association With Gemtuzumab Ozogamicin Response: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531.

1 reference

12 December 2020

Gemtuzumab Ozogamicin Versus Best Supportive Care in Older Patients With Newly Diagnosed Acute Myeloid Leukemia Unsuitable for Intensive Chemotherapy: Results of the Randomized Phase III EORTC-GIMEMA AML-19 Trial

1 reference

12 December 2020

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits

1 reference

12 December 2020

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

1 reference

12 December 2020

The level of blast CD33 expression positively impacts the effect of gemtuzumab ozogamicin in patients with acute myeloid leukemia

1 reference

12 December 2020

Expression and functional characterization of CD33 transcript variants in human acute myeloid leukemia

1 reference

12 December 2020

Expression of CD33 is a predictive factor for effect of gemtuzumab ozogamicin at different doses in adult acute myeloid leukaemia

1 reference

12 December 2020

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

1 reference

12 December 2020

An anti-CD3/anti-CLL-1 bispecific antibody for the treatment of acute myeloid leukemia

1 reference

12 December 2020

CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531.

1 reference

12 December 2020

The Alzheimer's Disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool

1 reference

12 December 2020

One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells.

1 reference

12 December 2020

Chimeric antigen receptor T-cell therapies for lymphoma

1 reference

12 December 2020

Integrating Proteomics and Transcriptomics for Systematic Combinatorial Chimeric Antigen Receptor Therapy of AML.

1 reference

12 December 2020

Treatment of relapsed AML and MDS after allogeneic stem cell transplantation with decitabine and DLI-a retrospective multicenter analysis on behalf of the German Cooperative Transplant Study Group.

1 reference

12 December 2020

Immune therapies in acute myeloid leukemia: a focus on monoclonal antibodies and immune checkpoint inhibitors

1 reference

12 December 2020

No evidence that CD33 splicing SNP impacts the response to GO in younger adults with AML treated on UK MRC/NCRI trials.

1 reference

12 December 2020

CD33 splicing SNP regulates expression levels of CD33 in normal regenerating monocytes in AML patients.

1 reference

12 December 2020

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.

1 reference

12 December 2020

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia.

1 reference

12 December 2020

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.

1 reference

12 December 2020

Identifiers

DOI

10.3389/FONC.2018.00539

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30524966%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30524966%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

30524966

1 reference