(Q60045001)

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Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways

scientific article published on 13 December 2018

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scholarly article

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14 April 2020

Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways (English)

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14 April 2020

molecular biology

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Benoît Tessoulin

1

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14 April 2020

Agnes Moreau-Aubry

2

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14 April 2020

Philippe Moreau

10

object named as

Philippe Moreau

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14 April 2020

author name string

Géraldine Descamps

3

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14 April 2020

Patricia Gomez-Bougie

4

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14 April 2020

Sophie Maïga

5

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14 April 2020

Alban Gaignard

6

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14 April 2020

David Chiron

7

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14 April 2020

Emmanuelle Ménoret

8

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14 April 2020

Steven Le Gouill

9

1 reference

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14 April 2020

Martine Amiot

11

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14 April 2020

Catherine Pellat-Deceunynck

12

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14 April 2020

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publication date

13 December 2018

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14 April 2020

Journal of Hematology & Oncology

1 reference

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14 April 2020

11

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14 April 2020

137

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14 April 2020

1

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14 April 2020

copyright license

Creative Commons Attribution 4.0 International

1 December 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

describes a project that uses

object named as

limma

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

https://scigraph.springernature.com/pub.10.1186/s13045-018-0679-0

0 references

DNA protein cross-links produced by NSC 652287, a novel thiophene derivative active against human renal cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

False human hematopoietic cell lines: cross-contaminations and misinterpretations

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular classification of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hallmarks of Cancer: The Next Generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial genome sequencing and analysis of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A diverse range of gene products are effectors of the type I interferon antiviral response

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABT-737 is highly effective against molecular subgroups of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

clusterProfiler: an R package for comparing biological themes among gene clusters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death via DR5, but not DR4, is regulated by p53 in myeloma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high-performance computing toolset for relatedness and principal component analysis of SNP data

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bendamustine and melphalan kill myeloma cells similarly through reactive oxygen species production and activation of the p53 pathway and do not overcome resistance to each other.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination of international scoring system 3, high lactate dehydrogenase, and t(4;14) and/or del(17p) identifies patients with multiple myeloma (MM) treated with front-line autologous stem-cell transplantation at high risk of early MM progression-r

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53abnormal myeloma cells independently of the p53 pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PRIMA-1Met induces myeloma cell death independent of p53 by impairing the GSH/ROS balance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Whole-exome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dexamethasone-induced cell death is restricted to specific molecular subgroups of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compendium of FAM46C gene mutations in plasma cell dyscrasias.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ReactomePA: an R/Bioconductor package for reactome pathway analysis and visualization

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic complexity of multiple myeloma and its clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A DNA target-enrichment approach to detect mutations, copy number changes and immunoglobulin translocations in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

False and mycoplasma-contaminated leukemia-lymphoma cell lines: time for a reappraisal

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How have evolutions in strategies for the treatment of relapsed/refractory multiple myeloma translated into improved outcomes for patients?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of systemic administration of Edmonston strain of measles virus genetically engineered to express the sodium iodide symporter in patients with recurrent or refractory multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase 4/6 inhibitors in hormone receptor-positive early breast cancer: preliminary results and ongoing studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once Thought

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secondary plasma cell leukemia: a multicenter retrospective study of 101 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maftools: efficient and comprehensive analysis of somatic variants in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 regulates CD46 expression and measles virus infection in myeloma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30545397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13045-018-0679-0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30545397%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13045-018-0679-0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30545397%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30545397%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

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