(Q60197481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22419605%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Synthesis, biological activity, and ADME properties of novel S-DABOs/N-DABOs as HIV reverse transcriptase inhibitors (English)

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26 January 2020

1

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26 January 2020

José A. Esté

13

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26 January 2020

Bonaventura Clotet Sala

12

object named as

Bonaventura Clotet

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26 January 2020

Giovanni Maga

9

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ORCID Public Data File 2021

Maurizio Botta

14

object named as

Maurizio Botta

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26 January 2020

8

Elena Dreassi

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26 January 2020

author name string

Mafalda Pagano

2

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26 January 2020

Luigi Franchi

3

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26 January 2020

Daniele Castagnolo

4

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26 January 2020

Silvia Schenone

5

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26 January 2020

Gianni Casaluce

6

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26 January 2020

Claudio Zamperini

7

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26 January 2020

Alberta Samuele

10

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26 January 2020

Encarna Gonzalo

11

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26 January 2020

publication date

14 March 2012

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26 January 2020

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26 January 2020

volume

7

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26 January 2020

issue

5

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26 January 2020

page(s)

883-896

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Nonnucleoside reverse transcriptase inhibitor resistance and the role of the second-generation agents

26 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009).

1 reference

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7 January 2021

Development of topical microbicides to prevent the sexual transmission of HIV

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7 January 2021

Update on microbicide research and development - seeking new HIV prevention tools for women

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7 January 2021

Advances in HIV microbicide development

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7 January 2021

Novel tight binding PETT, HEPT and DABO-based non-nucleoside inhibitors of HIV-1 reverse transcriptase

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7 January 2021

Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Novel broad-spectrum thiourea non-nucleoside inhibitors for the prevention of mucosal HIV transmission

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor

1 reference

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7 January 2021

Carrageenan/MIV-150 (PC-815), a combination microbicide

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7 January 2021

In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1

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7 January 2021

Dawn of non-nucleoside inhibitor-based anti-HIV microbicides

1 reference

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7 January 2021

Recent advances in the DABOs family as potent HIV-1 non-nucleoside reverse transcriptase inhibitors

1 reference

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7 January 2021

Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile

1 reference

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7 January 2021

Recent highlights in the synthesis of highly functionalized pyrimidines

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase

1 reference

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7 January 2021

Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.

1 reference

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7 January 2021

A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs

1 reference

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7 January 2021

A general, Brønsted acid-catalyzed hetero-Michael addition of nitrogen, oxygen, and sulfur nucleophiles

1 reference

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7 January 2021

An Improved One-pot Procedure for the Synthesis of Alkynes from Aldehydes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Compensatory mutations rescue the virus replicative capacity of VIRIP-resistant HIV-1.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200056

7 January 2021

High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes

1 reference

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7 January 2021

High throughput prediction of oral absorption: improvement of the composition of the lipid solution used in parallel artificial membrane permeation assay

1 reference

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7 January 2021

Identifiers

DOI

10.1002/CMDC.201200056

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22419605%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference