(Q60686091)

English

5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions

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scholarly article

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5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions (English)

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neuropathic pain

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inferred from title

object named as

Livio Luongo

1

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author name string

Riccardo Petrelli

2

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Luisa Gatta

3

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Catia Giordano

4

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Francesca Guida

5

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Patrizia Vita

6

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Palmarisa Franchetti

7

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Mario Grifantini

8

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Vito de Novellis

9

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Loredana Cappellacci

10

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Sabatino Maione

11

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language of work or name

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publication date

22 November 2012

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17

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12

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13712-26

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copyright license

Creative Commons Attribution 4.0 International

22 November 2012

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April 2022 Public Data File from Crossref

copyright status

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The liberation of fractalkine in the dorsal horn requires microglial cathepsin S.

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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The induction of pain: an integrative review

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Diminished adenosine A1 receptor expression on macrophages in brain and blood of patients with multiple sclerosis

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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The antinociceptive effects of the systemic adenosine A1 receptor agonist CPA in the absence and in the presence of spinal cord sensitization

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Cathepsin S release from primary cultured microglia is regulated by the P2X7 receptor

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

based on heuristic

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Adenosine agonists reduce voltage-dependent calcium conductance of mouse sensory neurones in cell culture

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS.

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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The antinociceptive effect of 2-chloro-2′-C-methyl-N6-cyclopentyladenosine (2′-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the rat

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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A 2A adenosine receptor regulates glia proliferation and pain after peripheral nerve injury

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Pain-basic principles of management

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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A1 adenosine receptors in microglia control glioblastoma-host interaction

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice.

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity.

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Increased nociceptive response in mice lacking the adenosine A1 receptor

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Antinociceptive effects of novel A2B adenosine receptor antagonists.

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Regulation of Notch signaling during T- and B-cell development by O-fucose glycans

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Differential expression of adenosine receptors in human neutrophils: up-regulation by specific Th1 cytokines and lipopolysaccharide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Activated microglia contribute to the maintenance of chronic pain after spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Spinal microglia and neuropathic pain in young rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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1-(2′,4′-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular effects of adenosine and its analogs in anaesthetized rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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The antiinflammatory effects of methotrexate are mediated by adenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A1 receptors ligands: past, present and future trends

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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Adenosine-activated potassium conductance in cultured striatal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

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5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

based on heuristic

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Pain-relieving prospects for adenosine receptors and ectonucleotidases

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https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

based on heuristic

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N6-Cycloalkyl- and N6-bicycloalkyl-C5'(C2')-modified adenosine derivatives as high-affinity and selective agonists at the human A1 adenosine receptor with antinociceptive effects in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23174891

12 December 2020

based on heuristic

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Identifiers

10.3390/MOLECULES171213712

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