(Q60705900)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Imipramine demethylation in vivo: impact of CYP1A2, CYP2C19, and CYP3A4 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Kim Brosen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

B B Rasmussen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

0 references

publication date

1 March 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

2 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

61

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

319-324

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

Imipramine demethylation and hydroxylation: impact of the sparteine oxidation phenotype

2 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Steady-state levels of imipramine and its metabolites: significance of dose-dependent kinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Imipramine metabolism in relation to the sparteine and mephenytoin oxidation polymorphisms--a population study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Imipramine metabolism in man. A study of urinary metabolites after administration of radioactive imipramine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

The role of S-mephenytoin 4'-hydroxylase in imipramine metabolism by human liver microsomes: a two-enzyme kinetic analysis of N-demethylation and 2-hydroxylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Fluvoxamine is a potent inhibitor of cytochrome P4501A2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Inhibitors of imipramine metabolism by human liver microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Interaction between fluvoxamine and imipramine/desipramine in four patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Determination of urinary metabolites of caffeine for the assessment of cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activity in humans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

A urinary metabolite ratio that reflects systemic caffeine clearance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Determination of theophylline and its metabolites in human urine and plasma by high-performance liquid chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

A fluvoxamine-caffeine interaction study

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Mephenytoin and sparteine oxidation: genetic polymorphisms in Denmark

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Proguanil metabolism is determined by the mephenytoin oxidation polymorphism in Vietnamese living in Denmark

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Chloroguanide metabolism in relation to the efficacy in malaria prophylaxis and the S-mephenytoin oxidation in Tanzanians.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Simultaneous determination of urinary free cortisol and 6β-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Determination of quinidine, dihydroquinidine, (3S)-3-hydroxyquinidine and quinidine N-oxide in plasma and urine by high-performance liquid chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

High-performance liquid chromatography of imipramine and six metabolites in human plasma and urine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Noninvasive tests of CYP3A enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

Phenytoin causes a rapid increase in 6 beta-hydroxycortisol urinary excretion in humans--a putative measure of CYP3A induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

The use of caffeine for enzyme assays: a critical appraisal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990164-8

10.1016/S0009-9236(97)90164-8

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9084457%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference