(Q60877151)

English

L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia

scientific article published on 08 December 2014

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482130%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia (English)

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24 February 2020

lymphoblastic leukemia

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Véronique Imbert

3

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24 February 2020

Emmanuel Griessinger

4

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24 February 2020

Damien Ambrosetti

10

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24 February 2020

Béatrice Bailly-Maitre

12

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24 February 2020

author name string

C Rosilio

1

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24 February 2020

M Nebout

2

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24 February 2020

Z Neffati

5

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24 February 2020

J Benadiba

6

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24 February 2020

T Hagenbeek

7

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24 February 2020

H Spits

8

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24 February 2020

J Reverso

9

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24 February 2020

J-F Michiels

11

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24 February 2020

H Endou

13

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24 February 2020

M F Wempe

14

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24 February 2020

J-F Peyron

15

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24 February 2020

publication date

8 December 2014

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24 February 2020

1 reference

Europe PubMed Central

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24 February 2020

29

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24 February 2020

6

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24 February 2020

1253-1266

1 reference

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PubMed publication ID

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24 February 2020

https://scigraph.springernature.com/pub.10.1038/leu.2014.338

0 references

T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted therapy in T-cell malignancies: dysregulation of the cellular signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure of amino acid homeostasis causes cell death following proteasome inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of L-type amino-acid transporter 1 (LAT1) in gastric carcinomas: comparison with non-cancerous lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD98hc (SLC3A2) regulation of skin homeostasis wanes with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD98hc (SLC3A2) mediates integrin signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel therapies for peripheral T-cell non-Hodgkin's lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of CHOP/GADD153 in endoplasmic reticulum stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorine-18-alpha-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: a clinicopathologic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria as therapeutic targets for cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

l-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hallmarks of Cancer: The Next Generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-type amino acid transporter 1 inhibitors inhibit tumor cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The paradox of the unfolded protein response in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting autophagy to fight hematopoietic malignancies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bidirectional transport of amino acids regulates mTOR and autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of L-type amino acid transporter 1 (LAT1) in esophageal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and pharmacokinetic studies of JPH203, an L-amino acid transporter 1 (LAT1) selective compound

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of L-type amino acid transporter 1 and CD98 expression with triple negative breast cancer prognosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD98 increases renal epithelial cell proliferation by activating MAPKs

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unfolded protein response: from stress pathway to homeostatic regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tenets of PTEN tumor suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular pathogenesis of T-cell leukaemia and lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25482130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/LEU.2014.338

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482130%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482130%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

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