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Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells
scientific article published on 25 January 2011
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
title
Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
main subject
lymphoblastic leukemia
1 reference
based on heuristic
inferred from title
acute T cell leukemia
1 reference
based on heuristic
inferred from title
author
Lidia Moserle
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Luca Persano
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Valentina Agnusdei
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Valeria Tosello
series ordinal
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Giuseppe Basso
series ordinal
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Stefano Indraccolo
series ordinal
10
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
author name string
M Masiero
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
S Minuzzo
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
I Pusceddu
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
A Amadori
series ordinal
9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
publication date
25 January 2011
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
published in
Leukemia
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
volume
25
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
page(s)
588-598
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/leu.2010.323
0 references
cites work
Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
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7 January 2021
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Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.
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7 January 2021
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The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
1 reference
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https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
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Notches, NFkappaBs and the making of T cell leukemia.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular pathogenesis of T-cell leukaemia and lymphoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
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inferred from DOI database lookup
Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
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Models, mechanisms and clinical evidence for cancer dormancy
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7 January 2021
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Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
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inferred from DOI database lookup
Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer
1 reference
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https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
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inferred from DOI database lookup
Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment.
1 reference
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7 January 2021
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Dynamic bioluminescence imaging for quantitative tumour burden assessment using IV or IP administration of D: -luciferin: effect on intensity, time kinetics and repeatability of photon emission.
1 reference
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https://api.crossref.org/works/10.1038%2FLEU.2010.323
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Interferon-alpha gene therapy by lentiviral vectors contrasts ovarian cancer growth through angiogenesis inhibition
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for mitogen-activated protein (MAP) kinase phosphatase-1 in stress-responsive MAP kinase and cell survival signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of Dual-Specificity Phosphatases Is Involved in the Regulation of Extracellular Signal-Regulated Kinases by Heat Shock and Hsp72
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-small-cell lung cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAPK phosphatases--regulating the immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual-specificity MAP kinase phosphatases (MKPs) and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
MKP-1 is necessary for T cell activation and function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
p38 MAP kinase's emerging role as a tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
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7 January 2021
based on heuristic
inferred from DOI database lookup
A radical role for p38 MAPK in tumor initiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch3, another Notch in T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notchless T cell maturation?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch signaling suppresses p38 MAPK activity via induction of MKP-1 in myogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.323
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/LEU.2010.323
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Dimensions Publication ID
1007152732
0 references
PubMed publication ID
21263446
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21263446
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21263446%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
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