(Q35941622)

11 August 2017

1 reference

title

p38 MAP kinase's emerging role as a tumor suppressor (English)

1 reference

11 August 2017

Dmitry V Bulavin

1

1 reference

PubMed ID

15530558

11 August 2017

Albert J Fornace

series ordinal

2

1 reference

11 August 2017

1 January 2004

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Advances in Cancer Research

11 August 2017

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11 August 2017

92

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11 August 2017

95-118

1 reference

Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development

11 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Negative feedback regulation of MKK6 mRNA stability by p38alpha mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Mammalian G1- and S-phase checkpoints in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Mechanism of p38 MAP kinase activation in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

p38 and Chk1 kinases: different conductors for the G(2)/M checkpoint symphony

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Replicative senescence: an old lives' tale?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Role of the Cdc25A phosphatase in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Osmotic stress regulates the stability of cyclin D1 in a p38SAPK2-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Chk1 Kinase Negatively Regulates Mitotic Function of Cdc25A Phosphatase through 14-3-3 Binding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Feedback control of the protein kinase TAK1 by SAPK2a/p38

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

CD40-CD40L interactions induce chemokine expression by human microglia: implications for human immunodeficiency virus encephalitis and multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

MAPK pathways in radiation responses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

CDC25 phosphatases as potential human oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Mixed-lineage kinase control of JNK and p38 MAPK pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Polycomb CBX7 has a unifying role in cellular lifespan

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Selective p38 activation in human non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Human p53 is phosphorylated on serines 6 and 9 in response to DNA damage-inducing agents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Regulation of Bax translocation through phosphorylation at Ser-70 of Bcl-2 by MAP kinase in NO-induced neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Gadd45a contributes to p53 stabilization in response to DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

The p38 MAP kinase signaling pathway in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

The p38 Mitogen-Activated Protein Kinase Pathway Links the DNA Mismatch Repair System to the G2 Checkpoint and to Resistance to Chemotherapeutic DNA-Methylating Agents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Osmotic shock induces G1 arrest through p53 phosphorylation at Ser33 by activated p38MAPK without phosphorylation at Ser15 and Ser20.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Oligomerization of human Gadd45a protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Protein kinase CK2 in mammary gland tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

ICAM-1-induced expression of proinflammatory cytokines in astrocytes: involvement of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Three distinct signalling responses by murine fibroblasts to genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Genes involved in senescence and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Rapid destruction of human Cdc25A in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Integrating stress-response and cell-cycle checkpoint pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Phosphorylation Sites on Tau Identified by Nanoelectrospray Mass Spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Role of NF-κB in p53-mediated programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Phosphorylation site interdependence of human p53 post-translational modifications in response to stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Regulation of p73 by c-Abl through the p38 MAP kinase pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

A role for both RB and p53 in the regulation of human cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

In the cellular garden of forking paths: how p38 MAPKs signal for downstream assistance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Hepatitis B virus X protein activates the p38 mitogen-activated protein kinase pathway in dedifferentiated hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

The tumor-suppressive functions of the human INK4A locus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

The Transcriptional Repressor HBP1 Is a Target of the p38 Mitogen-Activated Protein Kinase Pathway in Cell Cycle Regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Specific protection against breast cancers by cyclin D1 ablation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2804%2992005-2

7 January 2021

10.1016/S0065-230X(04)92005-2

Identifiers

DOI

0 references

PubMed ID

15530558

1 reference

PubMed ID

15530558