(Q61453566)

English

Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-κB-mediated induction of XIAP

scientific article published on 10 September 2009

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763917%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin (English)

1 reference

Europe PubMed Central

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7 February 2020

arsenic trioxide

0 references

acute promyelocytic leukemia

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Majid Zaki-Dizaji

2

1 reference

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7 February 2020

Ahmad R. Dehpour

4

1 reference

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7 February 2020

9

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7 February 2020

Maryam Rahimi-Balaei

5

object named as

Maryam Rahimi-Balaei

1 reference

Europe PubMed Central

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7 February 2020

1

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Majid Momeny

1 reference

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7 February 2020

Kamran Alimoghaddam

8

object named as

Kamran Alimoghaddam

1 reference

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7 February 2020

Ardeshir Ghavamzadeh

7

object named as

Ardeshir Ghavamzadeh

1 reference

Europe PubMed Central

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7 February 2020

Yassan Abdolazimi

6

object named as

Yassan Abdolazimi

1 reference

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7 February 2020

author name string

Reza Ghasemi

3

1 reference

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7 February 2020

publication date

10 September 2009

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7 February 2020

Medical Oncology

1 reference

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7 February 2020

27

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7 February 2020

833-842

1 reference

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7 February 2020

3

1 reference

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7 February 2020

https://scigraph.springernature.com/pub.10.1007/s12032-009-9294-9

0 references

Effects of arsenic trioxide on the cellular proliferation, apoptosis and differentiation of human neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB regulates the stability and activity of p73 by inducing its proteolytic degradation through a ubiquitin-dependent proteasome pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p73: Friend or foe in tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of acute promyelocytic leukemia with arsenic trioxide without ATRA and/or chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P63 and P73: P53 mimics, menaces and more

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TIP60 represses transcriptional activity of p73beta via an MDM2-bridged ternary complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: activation of caspases and down-regulation of Bcl-2 protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p53 gene family

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analyzing real-time PCR data by the comparative C(T) method

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IAP family proteins--suppressors of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipocalin 2 diminishes invasiveness and metastasis of Ras-transformed cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic trioxide, a novel mitochondriotoxic anticancer agent?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-leukemic and anti-angiogenesis efficacy of arsenic trioxide in new cases of acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemosensitivity linked to p73 function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic trioxide (As2O3) inhibits invasion of HT1080 human fibrosarcoma cells: role of nuclear factor-kappaB and reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinase is involved in the degradation of p53 protein in the bryostatin-1-induced differentiation of the acute promyelocytic leukemia NB4 cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic inhibition of telomerase transcription leads to genetic instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB in cancer: from innocent bystander to major culprit

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time PCR analysis of PML-RAR alpha in newly diagnosed acute promyelocytic leukaemia patients treated with arsenic trioxide as a front-line therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The alteration of mitochondria is an early event of arsenic trioxide induced apoptosis in esophageal carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenic trioxide prevents radiation-enhanced tumor invasiveness and inhibits matrix metalloproteinase-9 through downregulation of nuclear factor kappaB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TP53INP1 is a novel p73 target gene that induces cell cycle arrest and cell death by modulating p73 transcriptional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide-induced cell death in myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of p73 in malignancy: tumor suppressor or oncogene?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of the lipocalin 24p3 as an apoptotic mechanism for MK886.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenite induces p53 accumulation through an ATM-dependent pathway in human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IKK NF-kappa B system: a treasure trove for drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylation of the p53 DNA-binding domain regulates apoptosis induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of action of arsenic trioxide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of arsenic trioxide in patients with metastatic renal cell carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19763917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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