(Q61803782)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

1 reference

9 October 2020

The Immunology of Macrophage Activation Syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

0 references

0 references

macrophage activation syndrome

1 reference

9 October 2020

1 reference

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

Randy Quentin Cron

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

author name string

Courtney B Crayne

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

Kim E Nichols

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

language of work or name

English

0 references

publication date

1 February 2019

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

9 October 2020

Frontiers in Immunology

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

9 October 2020

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

page(s)

119

1 reference

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Creative Commons Attribution 4.0 International

23 April 2020

copyright license

1 reference

Correlation of serum interleukin-6 levels with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis

9 October 2020

cites work

1 reference

12 December 2020

Transforming growth factor beta downregulates interleukin-1 (IL-1)-induced IL-6 production by human monocytes.

1 reference

12 December 2020

The accelerated phase of Chediak-Higashi syndrome. An expression of the virus-associated hemophagocytic syndrome?

1 reference

12 December 2020

Acute hemorrhagic, hepatic, and neurologic manifestations in juvenile rheumatoid arthritis: possible relationship to drugs or infection

1 reference

12 December 2020

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

1 reference

12 December 2020

Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine

1 reference

12 December 2020

Efficacy of cyclosporine A in the treatment of macrophage activation syndrome in juvenile arthritis: report of five cases

1 reference

12 December 2020

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

1 reference

12 December 2020

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

1 reference

12 December 2020

Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus

1 reference

12 December 2020

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

1 reference

12 December 2020

Shedding of CD163, a novel regulatory mechanism for a member of the scavenger receptor cysteine-rich family

1 reference

12 December 2020

Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

1 reference

12 December 2020

CD8+ T Cell-Dependent Elimination of Dendritic Cells In Vivo Limits the Induction of Antitumor Immunity

1 reference

12 December 2020

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

1 reference

12 December 2020

Interleukin-18 induces production of proinflammatory cytokines in mice: no intermediate role for the cytokines of the tumor necrosis factor family and interleukin-1beta

1 reference

12 December 2020

Identification of the haemoglobin scavenger receptor.

1 reference

12 December 2020

Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia

1 reference

12 December 2020

Reactive haemophagocytic syndrome in children with inflammatory disorders. A retrospective study of 24 patients

1 reference

12 December 2020

Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma

1 reference

12 December 2020

Is macrophage activation syndrome a new entity?

1 reference

12 December 2020

Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model

1 reference

12 December 2020

Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome

1 reference

12 December 2020

Heme oxygenase-1: unleashing the protective properties of heme

1 reference

12 December 2020

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

1 reference

12 December 2020

An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder

1 reference

12 December 2020

Functional plasticity of macrophages: reversible adaptation to changing microenvironments

1 reference

12 December 2020

Macrophage activation syndrome: characteristic findings on liver biopsy illustrating the key role of activated, IFN-gamma-producing lymphocytes and IL-6- and TNF-alpha-producing macrophages

1 reference

12 December 2020

CD163: a specific marker of macrophages in paraffin-embedded tissue samples

1 reference

12 December 2020

Soluble hemoglobin-haptoglobin scavenger receptor CD163 as a lineage-specific marker in the reactive hemophagocytic syndrome.

1 reference

12 December 2020

Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome

1 reference

12 December 2020

Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11

1 reference

12 December 2020

Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

1 reference

12 December 2020

Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

1 reference

12 December 2020

Does systemic-onset juvenile idiopathic arthritis belong under juvenile idiopathic arthritis?

1 reference

12 December 2020

Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo

1 reference

12 December 2020

Lethal hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type II

1 reference

12 December 2020

Macrophage activation syndrome as the presenting manifestation of rheumatic diseases in childhood.

1 reference

12 December 2020

HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.

1 reference

12 December 2020

Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin.

1 reference

12 December 2020

The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis

1 reference

12 December 2020

Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis.

1 reference

12 December 2020

The lytic NK cell immunological synapse and sequential steps in its formation

1 reference

12 December 2020

Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome.

1 reference

12 December 2020

Mutations of the hemophagocytic lymphohistiocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic arthritis

1 reference

12 December 2020

Macrophage activation syndrome in rheumatic disease: what is the role of the antigen presenting cell?

1 reference

12 December 2020

Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms

1 reference

12 December 2020

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells

1 reference

12 December 2020

Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis.

1 reference

12 December 2020

Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis

1 reference

12 December 2020

Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation

1 reference

12 December 2020

Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.

1 reference

12 December 2020

Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients

1 reference

12 December 2020

Macrophage activation syndrome induced by etanercept in a patient with systemic sclerosis

1 reference

12 December 2020

Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications

1 reference

12 December 2020

Combination therapy of abatacept and anakinra in children with refractory systemic juvenile idiopathic arthritis: a retrospective case series

1 reference

12 December 2020

Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series

1 reference

12 December 2020

Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice

1 reference

12 December 2020

Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice.

1 reference

12 December 2020

Perforin is a critical physiologic regulator of T-cell activation

1 reference

12 December 2020

Hemophagocytosis causes a consumptive anemia of inflammation

1 reference

12 December 2020

Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients.

1 reference

12 December 2020

Amplification of the response to Toll-like receptor ligands by prolonged exposure to interleukin-6 in mice: implication for the pathogenesis of macrophage activation syndrome.

1 reference

12 December 2020

Decisions about dendritic cells: past, present, and future

1 reference

12 December 2020

Necrotizing fasciitis in a pediatric patient treated with etanercept and cyclosporine for macrophage activation syndrome.

1 reference

12 December 2020

Diagnostic accuracy of a specific cytokine pattern in hemophagocytic lymphohistiocytosis in children

1 reference

12 December 2020

Sensitivity and specificity of bone marrow hemophagocytosis in hemophagocytic lymphohistiocytosis

1 reference

12 December 2020

Making sense of the cytokine storm: a conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes

1 reference

12 December 2020

Critical imbalance of TNF-α and soluble TNF receptor 1 in a patient with macrophage activation syndrome: potential implications for diagnostics and treatment

1 reference

12 December 2020

Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis

1 reference

12 December 2020

Interferon-γ mediates anemia but is dispensable for fulminant toll-like receptor 9-induced macrophage activation syndrome and hemophagocytosis in mice

1 reference

12 December 2020

Reaching the threshold: a multilayer pathogenesis of macrophage activation syndrome

1 reference

12 December 2020

Update on the treatment of juvenile idiopathic arthritis

1 reference

12 December 2020

Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8(+) T cells and dendritic cells

1 reference

12 December 2020

Marrow assessment for hemophagocytic lymphohistiocytosis demonstrates poor correlation with disease probability

1 reference

12 December 2020

Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

1 reference

12 December 2020

Therapeutic role of anakinra, an interleukin-1 receptor antagonist, in the management of secondary hemophagocytic lymphohistiocytosis/sepsis/multiple organ dysfunction/macrophage activating syndrome in critically ill children*

1 reference

12 December 2020

Treatment of juvenile idiopathic arthritis: a revolution in care

1 reference

12 December 2020

Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency.

1 reference

12 December 2020

H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice

1 reference

12 December 2020

Hyperinflammation, rather than hemophagocytosis, is the common link between macrophage activation syndrome and hemophagocytic lymphohistiocytosis

1 reference

12 December 2020

Macrophage activation and polarization: nomenclature and experimental guidelines

1 reference

12 December 2020

Whole-exome sequencing reveals overlap between macrophage activation syndrome in systemic juvenile idiopathic arthritis and familial hemophagocytic lymphohistiocytosis

1 reference

12 December 2020

Genetic defects in cytolysis in macrophage activation syndrome.

1 reference

12 December 2020

Chimeric antigen receptor T cells for sustained remissions in leukemia

1 reference

12 December 2020

Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion

1 reference

12 December 2020

Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-γ receptor deficiency.

1 reference

12 December 2020

Macrophage Activation Syndrome in Patients with Systemic Juvenile Idiopathic Arthritis under Treatment with Tocilizumab.

1 reference

12 December 2020

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time.

1 reference

12 December 2020

Macrophage activation syndrome in the course of monogenic autoinflammatory disorders.

1 reference

12 December 2020

Dissecting the heterogeneity of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

1 reference

12 December 2020

1 reference

12 December 2020

Clinical features and correct diagnosis of macrophage activation syndrome.

1 reference

12 December 2020

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Coll

1 reference

12 December 2020

TNF Counterbalances the Emergence of M2 Tumor Macrophages

1 reference

12 December 2020

Pathogenesis of Hemophagocytic Lymphohistiocytosis

1 reference

12 December 2020

ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice

1 reference

12 December 2020

Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

1 reference

12 December 2020

Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis

1 reference

12 December 2020

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Coll

1 reference

12 December 2020

A Heterozygous RAB27A Mutation Associated with Delayed Cytolytic Granule Polarization and Hemophagocytic Lymphohistiocytosis.

1 reference

12 December 2020

Macrophage activation syndrome in the era of biologic therapy.

1 reference

12 December 2020

Biologics in Pediatric Rheumatology: Quo Vadis?

1 reference

12 December 2020

Macrophage Polarization.

1 reference

12 December 2020

Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition.

1 reference

12 December 2020

Physiological roles of macrophages

1 reference

12 December 2020

Biologic therapy modifies clinical and laboratory features of macrophage activation syndrome associated with systemic juvenile idiopathic arthritis.

1 reference

12 December 2020

Kawasaki Disease Complicated With Macrophage Activation Syndrome: A Systematic Review

1 reference

12 December 2020

Weathering a Macrophage Storm

1 reference

12 December 2020

Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome.

1 reference

12 December 2020

Characteristic elevation of soluble TNF receptor II : I ratio in macrophage activation syndrome with systemic juvenile idiopathic arthritis.

1 reference

12 December 2020

Hemophagocytic syndrome: primary forms and predisposing conditions

1 reference

12 December 2020

Macrophage Activation Syndrome: A Report of Two Cases and a Literature Review.

1 reference

12 December 2020

Interleukin-18: Biological properties and role in disease pathogenesis

1 reference

12 December 2020

Overview of the IL-1 family in innate inflammation and acquired immunity

1 reference

12 December 2020

The NLRC4 Inflammasome.

1 reference

12 December 2020

Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis

1 reference

12 December 2020

Unopposed IL-18 signaling leads to severe TLR9-induced macrophage activation syndrome in mice

1 reference

12 December 2020

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.

1 reference

12 December 2020

Features, Treatment and Outcomes of Macrophage Activation Syndrome in Childhood-onset Systemic Lupus Erythematosus.

1 reference

12 December 2020

MicroRNA networks associated with active systemic juvenile idiopathic arthritis regulate CD163 expression and anti-inflammatory functions in macrophages through two distinct mechanisms.

1 reference

12 December 2020

Novel UNC13D intronic variant disrupting a NFκB enhancer in a patient with recurrent macrophage activation syndrome and systemic juvenile idiopathic arthritis.

1 reference

12 December 2020

Convergent pathways of the hyperferritinemic syndromes.

1 reference

12 December 2020

Anakinra treatment in macrophage activation syndrome: a single center experience and systemic review of literature

1 reference

12 December 2020

Soluble CD163, a unique biomarker to evaluate the disease activity, exhibits macrophage activation in systemic juvenile idiopathic arthritis

1 reference

12 December 2020

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

1 reference

12 December 2020

Are the 2016 EULAR/ACR/PRINTO classification criteria for macrophage activation syndrome applicable to patients with adult-onset Still's disease?

1 reference

12 December 2020

Rapamycin as an Adjunctive Therapy for NLRC4 Associated Macrophage Activation Syndrome

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2019.00119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30774631%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

1 reference