(Q30626213)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Misty R Jenkins

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Jesse A Rudd-Schmidt

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Jamie A Lopez

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Kelly M Ramsbottom

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Stuart I Mannering

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Daniel M Andrews

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Ilia Voskoboinik

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

2 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

1 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

212

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

307-317

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

Familial hemophagocytic lymphohistiocytosis: when rare diseases shed light on immune system functioning

1 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Perforinopathy: a spectrum of human immune disease caused by defective perforin delivery or function.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Rapid and unidirectional perforin pore delivery at the cytotoxic immune synapse.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8(+) T cells and dendritic cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Imaging burst kinetics and spatial coordination during serial killing by single natural killer cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Dose-dependent effects of the caspase inhibitor Q-VD-OPh on different apoptosis-related processes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

A critical role for granzymes in antigen cross-presentation through regulating phagocytosis of killed tumor cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

The synapse and cytolytic machinery of cytotoxic T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Tumor resistance to apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Cytotoxic T-lymphocyte-mediated killing of human pancreatic islet cells in vitro

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Reciprocal activating interaction between natural killer cells and dendritic cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

IAP family proteins--suppressors of apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Bystander stimulation of T cells in vivo by cytokines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

T cell receptor antagonist peptides induce positive selection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties

20 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

In vivo evidence for dendritic cell lysis by NK cells: Hints on improving cancer vaccines by targeting NK cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

Heterogeneity of effector phenotype for acute phase and memory influenza A virus-specific CTL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

An efficient method for cloning human autoantigen-specific T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140964

Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354371

Familial and acquired hemophagocytic lymphohistiocytosis

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25732304

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Perforin and Granzymes Have Distinct Roles in Defensive Immunity and Immunopathology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25732304

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20140964

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25732304%20AND%20SRC:MED&resulttype=core&format=json