(Q46706728)

English

Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis

scientific article published in April 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

1 reference

based on heuristic

inferred from title

Ricky W Johnstone

6

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Joseph A. Trapani

9

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

author name string

Waterhouse NJ

1

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Sedelies KA

2

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Sutton VR

3

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Pinkoski MJ

4

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Thia KY

5

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Bird PI

7

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Green DR

8

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

publication date

1 April 2006

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Cell Death & Differentiation

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

13

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

4

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

607-618

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

21 January 2018

Cell death induced by granzyme C.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme M mediates a novel form of perforin-dependent cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic lymphocytes; instigators of dramatic target cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

CTL: Caspases Terminate Life, but that's not the whole story.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

HYPOTHESIS: CYTOTOXIC LYMPHOCYTE GRANULE SERINE PROTEASES ACTIVATE TARGET CELL ENDONUCLEASES TO TRIGGER APOPTOSIS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

A central role for Bid in granzyme B-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Dependence of granzyme B-mediated cell death on a pathway regulated by Bcl-2 or its viral homolog, BHRF1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of recombinant mouse perforin expressed in insect cells using the baculovirus system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunopurification of functional Asp-ase (natural killer cell granzyme B) using a monoclonal antibody

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression and purification of recombinant human granzyme B from Pichia pastoris

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

The (Holey) study of mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

A new quantitative assay for cytochrome c release in apoptotic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial Release of Pro-apoptotic Proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Electrical coupling and plasticity of the mitochondrial network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401772

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CDD.4401772

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16167065

ResearchGate publication ID

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