(Q28251140)

6

0 references

Mark J. Smyth

object named as

Mark J Smyth

7

0 references

author name string

Janice M Kelly

1

0 references

Nigel J Waterhouse

2

0 references

Erika Cretney

3

0 references

Kylie A Browne

Journal of Biological Chemistry

4

0 references

language of work or name

English

0 references

publication date

21 May 2004

0 references

published in

0 references

volume

279

0 references

issue

21

0 references

page(s)

22236-42

0 references

cites work

Granzymes: exogenous proteinases that induce target cell apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Proapoptotic functions of cytotoxic lymphocyte granule constituents in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Functional significance of the perforin/granzyme cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Activation-induced cell death in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Cytotoxic T lymphocytes: all roads lead to death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Nuclear war: the granzyme A-bomb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

The genes encoding NK cell granule serine proteases, human tryptase-2 (TRYP2) and human granzyme A (HFSP), both map to chromosome 5q11-q12 and define a new locus for cytotoxic lymphocyte granule tryptases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

The human Met-ase gene (GZMM): structure, sequence, and close physical linkage to the serine protease gene cluster on 19p13.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Long-range disruption of gene expression by a selectable marker cassette

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Granzyme B plays a critical role in cytotoxic lymphocyte-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Granzyme A initiates an alternative pathway for granule-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Cell death induced by granzyme C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Granzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Expression and purification of recombinant human granzyme B from Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Characterization of recombinant mouse perforin expressed in insect cells using the baculovirus system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

A new quantitative assay for cytochrome c release in apoptotic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Role of TNF family ligands in antitumor activity of natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

CTL: Caspases Terminate Life, but that's not the whole story.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Apoptotic pathways: paper wraps stone blunts scissors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Cutting edge: granzymes A and B are not essential for perforin-mediated tumor rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Cloning and characterization of cDNA clones encoding CD9 from Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Four deaths and a funeral: from caspases to alternative mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200

Dependence of granzyme B-mediated cell death on a pathway regulated by Bcl-2 or its viral homolog, BHRF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401670200