(Q57272593)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279544%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Dependence of granzyme B-mediated cell death on a pathway regulated by Bcl-2 or its viral homolog, BHRF1 (English)

1 reference

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6 November 2019

1 reference

Davis JE

1

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6 November 2019

Sutton VR

series ordinal

2

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6 November 2019

publication date

1 October 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279544%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

6 November 2019

published in

1 reference

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6 November 2019

volume

7

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6 November 2019

issue

10

1 reference

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6 November 2019

page(s)

973-983

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400725

6 November 2019

exact match

0 references

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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

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CTL granules: evolution of vesicles essential for combating virus infections

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Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

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A natural killer cell granule protein that induces DNA fragmentation and apoptosis

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Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

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Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis

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Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction

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Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases

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Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

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The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32

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Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

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21 January 2018

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Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

21 January 2018

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Prevention of apoptosis by a baculovirus gene during infection of insect cells

21 January 2018

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Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death.

21 January 2018

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Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

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Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent

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BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis

21 January 2018

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Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing

21 January 2018

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Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis

21 January 2018

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BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

21 January 2018

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Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21ras function

21 January 2018

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21 January 2018

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The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes

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In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells

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21 January 2018

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Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia

21 January 2018

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Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes

21 January 2018

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The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

21 January 2018

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Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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7 January 2021

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

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7 January 2021

Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene

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7 January 2021

Regulation of Fas(Apo-1/CD95)- and perforin-mediated lytic pathways of primary cytotoxic T lymphocytes by the protooncogene bcl-2

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7 January 2021

Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400725

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279544%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference