(Q45169973)

10 December 2017

title

A central role for Bid in granzyme B-induced apoptosis (English)

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10 December 2017

11

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10 December 2017

Jane Oliaro

8

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Joseph A. Trapani

object named as

Joseph A Trapani

12

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Phillip I. Bird

object named as

Phillip I Bird

10

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author name string

Nigel J Waterhouse

1

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10 December 2017

Karin A Sedelies

2

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10 December 2017

Kylie A Browne

3

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10 December 2017

Michelle E Wowk

4

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10 December 2017

Andrea Newbold

5

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10 December 2017

Vivien R Sutton

6

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10 December 2017

Chris J P Clarke

7

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10 December 2017

Ralph K Lindemann

9

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10 December 2017

language of work or name

English

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publication date

1 December 2004

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Journal of Biological Chemistry

10 December 2017

published in

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10 December 2017

volume

280

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10 December 2017

issue

6

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10 December 2017

page(s)

4476-4482

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Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

10 December 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M410985200

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Expression and purification of recombinant human granzyme B from Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

A new quantitative assay for cytochrome c release in apoptotic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

The genes for perforin, granzymes A-C and IFN-gamma are differentially expressed in single CD8(+) T cells during primary activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Profiling the CD8low phenotype, an alternative career choice for CD8 T cells during primary differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Proteinase inhibitor 9, an inhibitor of granzyme B-mediated apoptosis, is a primary estrogen-inducible gene in human liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

Dependence of granzyme B-mediated cell death on a pathway regulated by Bcl-2 or its viral homolog, BHRF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410985200

21 January 2018

Identifiers

DOI

10.1074/JBC.M410985200

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10 December 2017

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